Reveal the pathological characteristics and outpatient clues of coVID-19 moderate patients!

, June 7, 2020 /
BioValleyBIOON/-- Since the early days of the COVID-19 pandemic, scientific literature and news reports have focused a great deal of attention on two types of patients: those who develop critical lysis and require intensive care, and those with asymptomatic infections or mild symptomsthese reports largely ignore another important category of patients -- those whose symptoms are so severe that they need to seek treatment but do not need hospital treatmentnow, researchers at Harvard Medical School and the Harvard-affiliated Cambridge Health Alliance have conducted a new analysis that provides insight into the category between the two, based on data collected by patients attending THE COVID-19 clinic in the Greater Boston areathe team's observations were recently published in the mayo Clinic ProceedingsThe study is based on data from more than 1,000 patients with respiratory diseases since COVID-19 was declared a pandemic in Marchpicture source: These findings provide a series of clues that could help clinicians distinguish between patients infected with COVID-19 and those with other conditions that may have symptoms similar to COVID-19the team says these leads are critical because even if detection is now more extensive than in the early days of the pandemic, early triage and rapid decision-making are still criticalTesting is far from universal, and even if it is available, it can take one to three daysIn addition, some of the rapid field detectionmethods that have emerged on the market are not entirely reliable and result in false negative readings"Early identification and appropriate treatment are particularly important because patients infected with SARS-CoV-2 may experience symptoms similar to those of various other acute viral andbacterialinfections," said study lead author DrPieter Cohen, an associate professor at Harvard Medical School and a doctor at the Cambridge Health Alliance"Even when fielddiagnostictests can be performed, understanding the early natural history of COVID-19 and good old-fashioned clinical skills will remain essential for proper care, taking into account the potential for false negative results." Theadded that a detailed understanding of the typical performance of COVID-19 in outpatients could also help clinicians determine how often they are reviewed with patientsFor example, patients who have begun to develop shortness of breath need very close monitoring and frequent follow-up to check how shortness of breath evolves and whether the patient may be in the hospital for a worseningaccording to the report, COVID-19 usually manifests itself as a symptom of a viral infection, usually accompanied by low fever, cough and fatigue, and less gastrointestinal problemsShortness of breath usually occurs a few days after the initial symptoms and becomes most pronounced during force, possibly involving a sharp drop in blood oxygen levelsteam's main findings include:fever is not a reliable indicator, if present, it can only appear as a slight increase in temperature;COVID-19 may start in a variety of order of coughing, without fever cough, sore throat, diarrhea, abdominal pain, headache, body pain, back pain and fatigue;can also develop severe physical pain and fatigue;a reliable early warning is lost in the first few days of the onset of the diseaseshortness of breath is an important difference from other common diseases in severe COVID-19,however, almost no one develops shortness of breath in the first day or two of the onset, which is the main symptom of the disease, shortness ofshortness of breath can occur 4 days or more after the onset of other symptoms, andshortness of breath is a critical period, requiring close and frequent monitoring of the patient through telemedicine or personal examination;The most critical variable for monitoring is how shortness of breath changes over time, and oxygen saturation levels are a valuable clueEven people who were previously healthy have a sharp drop in blood oxygen levels during the process of exerting force; a small percentage of people may never develop shortness of breath, but may experience other symptoms that may indicate low oxygen levels, including dizziness or falls; and anxiety - common in anxious patients with suspected SYMPTOMs of THE COVID-19 virus - can also cause shortness of breath picture source: It is vital to distinguish between anxiety-induced shortness of breath and COVID-19-related shortness of breath There are several ways to distinguish between the two the main differences include: time to start a disease: anxiety short attacks are rapid, seemingly sudden, while COVID-19 shortness tends to develop over a few days; patients' description of feelings: anxiety-induced shortness patients usually describe feelings that occur during rest or trying to fall asleep, but do not become more pronounced during daily activities, often describing feelings that do not have enough air to enter the lungs, compared to those that do not have enough air to enter the lungs Shortness of shortness caused by coVID-19-related hypoxia increases with physical activity, including simple daily activities such as walking, stair climbing, or cleaning; shortness of anxiety-related shortness of breath does not lead to a decrease in blood oxygen levels; and in clinical examination, a commonly used device, pulse oximeter, is valuable in distinguishing between the two When clamped on a finger, the device can measure blood oxygen levels and heart rate in a matter of seconds several types of pneumonia bears striking similarities to COVID-19 For example, the symptoms of the COVID-19 respiratory system appear to be very similar to those caused by pneumoconiosis, a lung infection that mainly affects the alveoli A licosis is a tiny air bag arranged on the surface of the lungs Patients with COVID-19 and patients with pneumoscosporidium spore pneumonia had an average sharp drop in oxygen levels during force and shortness of breath However, in the case of pneumoconiosis pneumonia, shortness of breath usually occurs unknowingly within weeks, rather than within days, as COVID-19 does A detailed description of the patient's medical history of the evolution of symptoms is critical, the authors say similarly, the , flu and COVID-19 may be the same in the first few days of infection, but since then there has been a difference between the two infections People with common flu rarely experience significant shortness of breath When they experience breathing difficulties, shortness of breath is mild and stable In rare cases of influenza-induced viral pneumonia, the patient's condition rapidly deteriorates within the first two to three days In contrast, patients with COVID-19 did not develop shortness of breath until a few days after the first onset of the disease (BioValleyBioon.com) References: -PatientCOVID-19 clues
Pieter A Cohen et al, The Early Natural History of SARS-CoV-2 Infection: Clinical Observations From An Urban, AmbulatoCOVID-19 Clinic , Mayo Clinic Proceedings (2020) DOI: 10.1016/j.mayocp.2020.04.010