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Lung cancer is one of the world's most deadly cancers, with about 80 percent of lung cancer deaths linked to smoking, and effective chemical prevention strategies are needed in addition to tobacco control, according to scientists at the University of Geneva in a recent study published in the international journal Scientology Reports. Resveratrol, a natural product of grapes and red wine, has been studied in depth, after many studies have found that the chemical prophylific properties of cancer can affect the digestive tract of patients, and so far resveratrol has not had any therapeutic effect on lung cancer. Now researchers have found in mice that nasal drugging may yield potential therapeutic results.in the
paper, the researchers tried to treat lung cancer in mice induced by carcinogens in cigarettes with resveratrol, and over a 26-week study, the researchers compared four groups of mice, the first of which received neither carcinogens nor resveratrol; In mice treated for carcinogens, the third group received both carcinogens and therapy, while the fourth group received treatment only, said researcher Muriel Cuendet. In mice in the treatment group, we found a 45 percent decrease in tumor load in each mouse body, and lower levels of tumor production and smaller size than in untreated mice. When the researchers compared two groups of mice that were not exposed to carcinogens, 63 percent of the mice in the treatment group did not develop cancer compared to the untreated mice (12.5 percent), so resveratrol may play a crucial preventive role in fighting lung cancer.This model is suitable for humans
however, resveratrol does not appear to be suitable for lung cancer prevention, and when it is ingested by the body, it is metabolized and eliminated within minutes, so it does not have enough time to reach the body's lungs; that is why researchers are constantly looking for a special formula in which researchers hope to make resveratrol soothing in water for nasal medicine;
Compared to oral methods, nasal dosing allows patients to achieve 22 times the concentration of resveratrol in the lungs of the former, a chemical prevention mechanism that appears to be primarily associated with apoptosis, and later researchers will use more in-depth research to find a specific biomarker to help researchers choose which patients are better suited to resveratrol's preventive therapy.
Resveratrol is a special molecule in the well-known health products, which means that prior to its commercialization, researchers did not need further toxicology research as a preventive treatment, resveratrol is very cheap and generic, although later researchers need to conduct more in-depth research to assess its key role in cancer prevention. (Bio Valley)