Researchers reveal the relationship between inflammation and tumor occurrence, development and treatment

Chinese researchers reveal the relationship between inflammation and tumor occurrence, development and treatment

Chinese researchers reveal the relationship between inflammation and tumor occurrence, development and treatment Chinese researchers reveal the relationship between inflammation and tumor occurrence, development and treatment

Xinhua News Agency, Chongqing, July 20 (Reporter Wentao Zhou) Inflammation is closely related to tumor occurrence, development and efficacy
.

Recently, Chinese researchers started with the initiation and regression of inflammation, systematically revealing the complex relationship between inflammation and tumorigenesis, development and treatment, and conducted an in-depth analysis of the types of inflammation that promote cancer and suppress cancer, and discussed in detail targeting Intervention strategies to regulate inflammation in tumor treatment

This research result, jointly conducted by the teams of Li Yongsheng and Wu Yongzhong from the Cancer Hospital of Chongqing University, was recently published in the international academic journal "Signal Transduction and Targeted Therapy"
.

According to reports, inflammation is divided into acute inflammation and chronic inflammation
.

Acute inflammation is the body's natural defense against damaged cells, viruses, and other harmful stimuli.

"Inflammation is
a'double -edged sword'.

How to regulate inflammation to improve the efficacy of cancer treatment is an important scientific issue in the current international frontier field .

The research team believes that some anti-inflammatory drugs can significantly reduce the incidence of cancer and the risk of death, and some pro-inflammatory cytokines or stimuli can promote the penetration of immune cells into infected tissues, thereby significantly improving the effect of tumor treatment
.

The use of non-specific anti-inflammatory drugs in the early stage can inhibit chronic inflammation, prevent the occurrence of tumors, and improve the killing effect of other therapies on tumor cells; antibodies are used for certain specific inflammatory mediators produced during tumor occurrence and treatment The method of neutralizing or targeting inhibition of inflammatory signal pathways can help improve the effects of anti-cancer therapies such as chemotherapy, radiotherapy, and immunotherapy

Li Yongsheng said that there are still many key issues that need to be solved urgently on how to regulate inflammation to improve the efficacy of cancer treatment
.

In addition, the different inflammatory responses of patients should also be considered in the anti-tumor process, and personalized treatment strategies for specific tumor-related inflammations will help improve the anti-cancer efficacy