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    Home > Food News > Food Articles > Researchers from the Institute of Feed, Chinese Academy of Agricultural Sciences analyzed the mechanism of Bacillus subtilis

    Researchers from the Institute of Feed, Chinese Academy of Agricultural Sciences analyzed the mechanism of Bacillus subtilis

    • Last Update: 2022-10-25
    • Source: Internet
    • Author: User
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    Recently, the feed resources and biotransformation team of the Feed Research Institute of the Chinese Academy of Agricultural Sciences revealed the molecular mechanism of Bacillus subtilis protecting meat ducks against E.
    coli infection and oxidative damage, providing technical support and theoretical basis
    for the establishment of animal antibiotic-free breeding technology system.
    The findings were published in the
    journal Antioxidants.
     
    Oxidative stress is caused by an imbalance between reactive oxygen species production and cellular antioxidant defenses, and is closely related to
    animal health.
    Oxidative stress caused by E.
    coli infection can lead to impaired health in meat ducks, significantly reduced production performance, and even death
    .
    Finding green, safe alternative feed additives to antibiotics that can effectively contain E.
    coli is imperative
    .
    Bacillus subtilis is considered a potential alternative to antibiotics due to its good bacteriostatic and antioxidant activity, however, Bacillus subtilis has been less
    studied and used in duck farming.
    In this study, the effects of Bacillus subtilis on the growth performance, antioxidant function and intestinal health of E.
    coli-infected ducks were analyzed by virginiamycin, and the molecular mechanism
    was elucidated.
    The results of the study showed that Bacillus subtilis can regulate the body's antioxidant capacity and energy metabolism by activating ribosomes and oxidative phosphorylation signaling pathways, thereby reducing the damage
    of E.
    coli infection to ducks.
     
    The research was supported
    by the Science and Technology Innovation Project of the Chinese Academy of Agricultural Sciences and the National Key R&D Program (Project).
     
    Original link: https://doi.
    org/10.
    3390/antiox11101951
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