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Research background
Study design
Study results
Conclusion of the study
Editor: Gardenia Reviewed: Gardenia Executive: Gardenia
A growing body of epidemiological evidence suggests that grip strength predicts physiological, psychological, and reproductive health status
.
What is the correlation between male grip strength and sperm quality? This article may give us some answers
.
Research background
Grip strength is one of
the indicators that reflect muscle function, strength, nutrition, and overall health.
Recent studies have demonstrated that lower grip strength is associated with
higher all-cause mortality, cardiovascular outcomes, diabetes prevalence, cognitive decline, and dysfunction.
Other studies have shown that there is a correlation between grip strength and male reproductive ability and testosterone concentration, but the relationship between grip strength and sperm quality is unclear and needs to be explored
.
In light of this, Chinese researchers investigated the grip strength and semen characteristics of 1382 healthy Chinese sperm donors to assess the potential value
of grip strength as a tool for predicting sperm quality.
Study design
The researchers recruited 1382 eligible healthy adult males at the Hubei Province Human Sperm Bank to collect general data on the participants at baseline and assess their grip strength
.
Participants were provided a total of 6458 semen specimens over 6 months, with sperm quality indicators including semen volume, sperm motility (motility graded into forward movement, non-forward movement, and inactivity), and sperm density
.
Statistically, the researchers applied a mixed-effects model and a restrictive cubic spline model to assess the relationship
between grip strength and repeated measurements of sperm quality.
Study results
The general demographic characteristics of participants stratified by quartile of grip strength are shown in Table 1
.
The median and interquartile range (IQR) of semen volume, sperm density, forward motility, total sperm motility and total count were 2.
9 (1.
5) ml, 48.
3×10 6 (31.
9×10 6)/ml, 57.
5% (13.
2%), 60.
8% (13.
2%), and 138.
6×106 (109.
3×10 6), respectively )
。 Compared with men in the lower quartile of grip strength, men in the upper quartile had a higher BMI (23.
7±3.
2 kg/m2 vs22.
3± 3.
3 kg/m2), shorter abstinence periods (6.
0±3.
3 d vs 6.
4±3.
6 days), and higher marriage rates (37.
6% vs 23.
1%)
.
Table 1 General demographic characteristics and sperm quality of participants stratified by quartile of grip strength
After adjusting for confounding factors, both the mixed-effects model (Table 2) and the restriction cubic spline model (Figure 1) showed that grip strength was positively correlated with semen volume, sperm density, forward motility sperm rate, total sperm motility, and total count (P<0.
05).
<b10> 。 Compared with men in the lower quartile of grip strength, men in the upper quartile had 14.
2% (95% CI: 5.
9% to 23.
2%), 19.
5% (95% CI: 7.
3% to 33.
1%), 9.
5% (95% CI: 3.
4% to 15.
9%), 8.
8% (95% CI: 3.
2% to 14.
6%) and 36.
4% (95% CI: 18.
9%- 56.
5%)
。
Table 2 is based on a mixed-effects model, grip strength (kg) versus sperm quality
Fig.
1 Relationship between grip strength (kg) and sperm quality
Conclusion of the study
Overall, the results showed that men's grip strength was positively correlated
with semen volume, sperm density, sperm motility, and total count.
As an objective and non-invasive indicator, grip strength is expected to be an effective predictive tool for assessing sperm quality, and its mechanism needs to be further explored
.
References:
Sun B, Chen HG, Duan P, Tu ZZ, Chen YJ, Meng TQ, Xiong CL, Wang YX, Pan A.
Association of handgrip strength with semen characteristics: a study with repeated measurements among healthy Chinese men.
Asian J Androl.
2022 Nov-Dec; 24(6):594-600.
doi: 10.
4103/aja20221.
PMID: 35381698.
Editor: Gardenia Reviewed: Gardenia Executive: Gardenia
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