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    Home > Active Ingredient News > Antitumor Therapy > Regent Bio announced the interim results of its phase 1 clinical study of the CD137/4-1BB agonist antibody LVGN6051 at the 2021 ASCO annual meeting

    Regent Bio announced the interim results of its phase 1 clinical study of the CD137/4-1BB agonist antibody LVGN6051 at the 2021 ASCO annual meeting

    • Last Update: 2021-06-10
    • Source: Internet
    • Author: User
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    Lijin Biomedical Technology Co.


    Immunity to ASCO

     

    The poster will summarize the mid-term safety and anti-tumor activity data of LVGN6051 as a single agent and its combination with PD-1 antibody observed in the Phase I clinical trial (NCT04130542) in the United States.


     

    The report details are as follows:

    Abstract number

    2521

    title

    Early safety and efficacy from a phase I open-label clinical trial of CD137 (4-1BB) agonistic antibody LVGN6051 as monotherapy and in combination with pembrolizumab

    Report session

    Developmental Therapeutics-Immunotherapy

    report time

    June 4, 2021, 9 a.


    Abstract number

    2521


    Early safety and efficacy from a phase I open-label clinical trial of CD137 (4-1BB) agonistic antibody LVGN6051 as monotherapy and in combination with pembrolizumab


    Developmental Therapeutics-Immunotherapy


    June 4, 2021, 9 a.



    2521

    Abstract number

    Abstract number

    Abstract number

    2521

    2521

    title

    Early safety and efficacy from a phase I open-label clinical trial of CD137 (4-1BB) agonistic antibody LVGN6051 as monotherapy and in combination with pembrolizumab

    title

    title

    title

    Early safety and efficacy from a phase I open-label clinical trial of CD137 (4-1BB) agonistic antibody LVGN6051 as monotherapy and in combination with pembrolizumab

    Early safety and efficacy from a phase I open-label clinical trial of CD137 (4-1BB) agonistic antibody LVGN6051 as monotherapy and in combination with pembrolizumab

    Report session

    Developmental Therapeutics-Immunotherapy

    Report session

    Report session

    Report session

    Developmental Therapeutics-Immunotherapy

    Developmental Therapeutics-Immunotherapy

    report time

    June 4, 2021, 9 a.


    report time

    report time

    report time

    June 4, 2021, 9 a.


    June 4, 2021, 9 a.


     

    AboutLVGN6051

    AboutLVGN6051

    The tumor immune target CD137 (4-1BB) targeted by LVGN6051 , activation of CD137 signal transduction can stimulate the proliferation of NK cells and T cells and produce anti-tumor activity, resulting in a lasting memory response.


    Tumor immunity

     

    About Lijin Bio

    About Lijin Bio

    Lyvgen was established in 2016 and settled in Shanghai Pudong Zhangjiang High-tech Park and Suzhou Industrial Park.




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