Reducing LDL-C may increase cancer risk
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Last Update: 2020-07-03
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Source: Internet
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Author: User
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high doses of statins may raise liver enzyme levels, while lower LDL-cholesterol (LDL-C) levels may increase the risk of cancer, U.SresearchersreportThe researchers analyzed data from 23 statin drug treatment branches in a forward-looking, randomized controlled clinical trialThese clinical trials involved a total of 75,317 patients who received different doses of statinsThe results showed that high doses of statins were accompanied by significantly increased increased liver enzyme levelsSignificantly, there is a highly inverse relationship between the achieved LDL-C level and the incidence of new cancer casesIn addition, there was a significant difference in the incidence of associated cancer between the high-dose statin group and the low- and medium-dose groups at every 10% reduction in LDL-CDrJC LaRosa of SUNY Downstate Medical Center in New York said the study's findings, while challenging, should only be considered a hypothesisData from other LDL-C clinical trials should be analyzed to provide more information, and further analysis should be supported by the National Institutes of Health (NIH)The editor of the AmericanHeartSociety (ACC), which published the study, agrees that it is appropriate to follow existing guidelines from the National Cholesterol Education Program (NCEP) before obtaining more dataAlthough the data for this study is incomplete, it suggests that further research and publication should be made public(Liu Min)
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