Radiology: The value of multiparametric MRI for risk stratification of renal masses

With increasing health awareness, more and more kidney masses are discovered incidentally on cross-sectional imagin.

In clinical practice, various methods have been proposed to differentiate benign and malignant SRMs and indolent and aggressive SRM.

Noninvasive imaging using CT or MRI for the diagnosis of renal mass subtypes in solid SRM is an alternative to biopsy and to some extent enables accurate diagnosis of some renal mass histopathological subtype.

The Clear Cell Likelihood Score (ccLS) system is a five-level Likert scale used to estimate the likelihood that an SRM is a ccRCC (1=very unlikely, 2=unlikely, 3=moderately likely, 4=likely, 5 = very likely.

Recently, a study published in the journal Radiology evaluated the performance and inter-observer agreement of the ccLS system in diagnosing ccRCC in solid SRM, and provided clinical evidence for accurate risk stratification and personalized treatment of such patient.

This retrospective multicenter study included consecutive patients with solid (≥25% approximate volume enhancement) SRM who underwent multiparametric MRI at five academic medical centers between December 2012 and December 2019 Histology confirmed the diagnosi.

A total of 250 solid SRMs with a mean size of 25 mm ± 8 (range, 10–39 mm) were evaluated in 241 patients (mean age, 60 years ± 13 [SD]; 174 males) in this stud.

This study demonstrates that the diagnostic performance of the Clear Cell Renal Cell Carcinoma (ccRCC) Likelihood Score (ccLS) system in assessing small solid renal masses meets clinical diagnostic need.

Original source:

Nicola Schieda, Matthew S Davenport, Stuart G Silverman, et a.