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Radiology: The Powerful Combination of CT+CA19-9: Evaluation of Treatment Response in Nonmetastatic Pancreatic Cancer

 Last Update: 2022-08-19
 Source: Internet
 Author: User

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It is well known that accurate assessment of treatment response is very important in the management of cancer patient.

With regard to pancreatic ductal adenocarcinoma (PDAC), CT has been the mainstay of treatment response assessmen.

A study published in the journal Radiology examined the effectiveness of combined assessment of CT (CT response) and CA 19-9 response in predicting overall survival (OS) in patients with non-metastatic PDAC at 8 weeks after initiation of first-line therap.

This study retrospectively enrolled patients with non-metastatic PDAC who received first-line chemotherapy or concurrent chemoradiation between January 2013 and December 2016 in a single-center PDAC cohort registr.

A total of 197 patients were evaluated (mean age ± SD, 65 years ± 10; 107 males.

This study demonstrates that the comprehensive evaluation of CT and CA 19-9 responses in this study is easy to apply in daily clinical practice, and can be more accurate in the early treatment of patients with non-metastatic pancreatic adenocarcinoma compared with the response evaluation criteria for solid tumor.

Original source:

Seung-Seob Kim, Sunyoung Lee, Hee Seung Lee, et a.

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