Radiology: Reduced hand movement restfunction function connection in glioma patients

Backgroundthe clinical application ofresting function MRI has great potential, but it is limited by the current understanding of the results of tumor resting function MRIpurposesthis study aims to explore the correlation between tumor, tumor characteristics, resting line changes, to explore the mechanism of the effect of neurovascular dissodycoupling on these changes, and to assess the applicability of Seeding methodology in clinical applicationsmaterials and methodsthis study included glioma patients with MRI and rest-function MRIAssess symmetry between the hemispheres of the hand movement area, including tumor location, perfusion, level, and seed-based correlation-based connection linesStatistical analysis was performed using T-test, Wilcoxon Level Sum Test, ANOVA, Pearson Correlation Analysis, and Spearman Level Correlation Analysisresultsstudy included a total of 45 glioma patients and 10 healthy control groupsCompared to the healthy control group, the restive connectivity symmetry of the patient's hand movement functional area disappeared (P.05)The degree of tumor and same-hand movement function (IHM) spacing and resting-state connectivity (R - 0.38, P s .01) and strength (R s 0.33, P s .03) are correlatedFor patients with glioma IV grade, tumor s/ iHM area is 40mm, and restive connectivity strength is associated with lateral damage and tumor perfusion (RIn patients with gliomadistance of IHM to 40mm, the effect of the asymmetry of the dynamic resting state of The Type of Non-Tumor Hemispheric Opponent was lower than that of the tumor hemisphereconclusion
in patients with glioma, the asymmetry of the restive connection of hand movement function has a distance from the tumorThe presence of neurovascular decoupling mechanisms may lead to a false negative result of resting-state connectivity differencesIn patients whoare to be closer to the hand movement functional area of the tumor, Seeding may have less asymmetry effect than the tumor side