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Radiology: Patients with COVID-19 infection have persistent white matter microstructure changes after one year of recovery

 Last Update: 2021-12-27
 Source: Internet
 Author: User

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There is increasing evidence that the severe acute respiratory syndrome coronavirus can affect the central nervous system
.

However, data on white matter and cognitive sequelae during the one-year follow-up are lacking

The team of Professor Liu Jun from the Department of Radiology of the Second Xiangya Hospital of Central South University and the team of Professor Luo Hong from Respiratory and Critical Care Medicine conducted relevant research and published research papers in the journal BRAIN
.

The study investigated 22 COVID-19 survivors and 21 matched healthy controls
.

Diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), neurite direction dispersion and density imaging (NODDI) were used to identify white matter changes, and the Webster’s intelligence subscale was used to assess cognitive function

COVID-19

Correlation between cognitive function and other clinical characteristics
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In addition, based on whether the patient was admitted to the ICU, a subgroup analysis was also performed.

In the rehabilitation group, the volume fraction of water in the cells of the radiation crown, corpus callosum and upper longitudinal tract was lower than that in the healthy control group
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The anisotropy score of the corpus callosum of ICU patients is lower than that of non-ICU patients

In the rehabilitation group, the volume fraction of water in the cells of the radiation crown, corpus callosum and upper longitudinal tract was lower than that in the healthy control group

With shorter hospital stays and longer follow-up times, white matter tends to have fewer abnormalities
.

With shorter hospital stays and longer follow-up times, white matter tends to have fewer abnormalities

After rehabilitation V COVID-19 of the year _ic value lower than HCs

Huang S, Zhou Z, Yang D, et al.

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