Radiology: Do you know this scoring system in predicting the progression of chronic hepatitis B HCC?

Hepatitis B virus (HBV) infection is one of the most common causes of end-stage liver disease such as cirrhosis, liver failure, and hepatocellular carcinoma (HCC)
.

The survey shows that more than 400 million people worldwide are chronically infected with HBV, and there are more than 90 million chronic hepatitis B (CHB) infections in China.

Hepatitis B virus (HBV) infection is one of the most common causes of end-stage liver disease such as cirrhosis, liver failure, and hepatocellular carcinoma (HCC)

Clinical scores currently using serological indicators-such as guiding age, gender, HBV DNA level, core promoter mutations and liver cirrhosis score (hereinafter referred to as GAG-HCC); HCC prediction constructed from liver cirrhosis, age, male sex and diabetes Score (hereinafter referred to as CAMD)

Online free use: liver cancer risk prediction for hepatitis B patients (GAG-HCC)

The liver stiffness measurement (LSM) obtained using transient elastography (TE) is a good assessment method for the development of HCC in the absence of cirrhosis , and has been included to improve the predictive performance of the HCC scoring system
.

HCC prediction score constructed by age, serum albumin level and HBV DNA level, namely LSM-HCC, and CHB score constructed by LSM, gender, age, alanine aminotransferase (ALT) level and hepatitis B e antigen positive (below (Referred to as mREACH-B) improved risk estimation

The liver stiffness measurement (LSM) obtained using transient elastography (TE) is a good assessment method for the development of HCC in the absence of cirrhosis , and has been included to improve the predictive performance of the HCC scoring system

Recently, published in the journal Radiology a study to assess the should behave with a perfect two-dimensional SWE in the development of HCC risk score predicted no clinical CHB patients with cirrhosis, and is clinically CHB patients provides strong early diagnosis and evaluation Strong means to support

Biopsy-proven CHB patients who underwent US and two-dimensional SWE between April 2011 and December 2015 were included in this study

Among 654 patients (mean age, 37 years; range, 30-43 years; 510 men), 26 developed HCC

 

The graph shows the accumulation of hepatocytes between low-risk ( HCC prediction constructed based on age, platelet count and two-dimensional shear wave elastography [APS score], less than 60 points) and high-risk (APS score greater than or equal to 60 points) patients Comparison of the development of HCC .
 

The graph shows the accumulation of hepatocytes between low-risk ( HCC prediction constructed based on age, platelet count and two-dimensional shear wave elastography [APS score], less than 60 points) and high-risk (APS score greater than or equal to 60 points) patients Comparison of the development of HCC .

，、APS（CHB）（HCC）

：

Ting Zhang,Genglin Zhang,Xinlei Deng,et al.

APS (Age, Platelets, 2D Shear-Wave Elastography) Score Predicts Hepatocellular Carcinoma in Chronic Hepatitis B.
DOI:10.
1148/radiol.
2021204700

Ting Zhang Genglin Zhang Xinlei Deng ,et al 10.
1148/radiol.
2021204700 10.
1148/radiol.

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