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    Home > Active Ingredient News > Antitumor Therapy > Radiology: Application of multi-parameter MRI in preoperative prediction of extraprostatic invasion

    Radiology: Application of multi-parameter MRI in preoperative prediction of extraprostatic invasion

    • Last Update: 2021-06-16
    • Source: Internet
    • Author: User
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    Extraprostatic invasion (EPE) is associated with positive surgical margins, local recurrence and survival rate after radical resection of male prostate cancer
    .
    Since the existence of EPE can affect the preservation of neurovascular bundles during surgery, the preoperative prediction of EPE is of great significance


    .


    Extraprostatic invasion (EPE) is associated with positive surgical margins, local recurrence and survival rate after radical resection of male prostate cancer


    Recently, a new MRI grading system for predicting EPE has been proposed clinically, called EPE grading


    In order to reduce the resection margin rate of positive surgical resection, the focus on multi-parameter MRI performance should turn to high sensitivity rather than high specificity.


    Recently, a study published in the journal Radiology compared classification, European Society of Urology and Reproductive Society (ESUR) score, Likert scale, and capsular contact length (CCL) to evaluate and predict the diagnosis of EPE after radical resection of prostate cancer.


    A total of 301 male patients (mean age ± standard deviation, 65 years ± 7 years) were evaluated
    .
    A total of 129 patients (42.


    9%) had EPE


    Compared with the EPE score , the Likert scale is less sensitive.


    Figure 1 The box plot shows the distribution of (ac) radial length and (df) week length of pathological extraprostatic invasion in each MRI evaluation category
    .
    The horizontal line in each box represents the middle value


    .


    Figure 1 The box plot shows the distribution of (ac) radial length and (df) week length of pathological extraprostatic invasion in each MRI evaluation category


    Table 1 The diagnostic performance of MRI-based evaluation of pathological extraprostatic invasion under a certain cut-off value


    .


    Table 1 The diagnostic performance of MRI-based evaluation of pathological extraprostatic invasion under a certain cut-off value


    In summary, this study verified and compared four methods for detecting extraprostatic invasion (EPE) on multi-parameter MRI


    Original source:

    Kye Jin Park , Mi-Hyun Kim , Jeong Kon Kim .
    Extraprostatic Tumor Extension: Comparison of Preoperative Multiparametric MRI Criteria and Histopathologic Correlation after Radical Prostatectomy .
    DOI: 10.
    1148/radiol.
    2020192133

    Jin Park Kye , Mi-Hyun Kim , Jeong Kim Kon .
    Extraprostatic Tumor Extension: Comparison of Preoperative MRI Criteria and Histopathologic Correlation Multiparametric the After Radical prostatectomy .
    DOI: 10.
    1148 / radiol.
    2020192133 10.
    1148 / radiol.
    2020192133 in this message
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