Quickly and sensitively identify multidrive bacteria

university in Basel, Switzerland, have developed a sensitive detection system that can quickly and reliably detect bacterial resistance. The system is based on tiny functional cantilevers that can be bent due to the combination of sample materials. In the analysis, the system was able to detect resistance in 1 to 10 bacterial samples.
bacteria that are no longer sensitive to antibiotics pose a major threat to people's health. In the case of bacterial infections, doctors need to quickly understand the potential for drug resistance so that they can respond quickly and correctly.
traditional methods of testing resistance are based on cultured bacteria and testing their sensitivity to a range of antibiotics. These methods take 48 to 72 hours to produce results, and some strains are difficult to cultivate. Molecular biology tests amplify specific short sequences of resistant genes or genetic material through polymerase chain reactions much faster, but even this approach does not provide satisfactory results for every bacteria.
small cantilevers, such as those that bend when RNA molecules are attached to its surface, and cantilevers can then be detected. RNA molecules are "transcripts" of genes that can act as instructions for building proteins. In addition, RNA molecules can be used to detect resistant genes in bacterial genetic material.
related papers were published recently in
. The system allows them to detect RNA from a single antibiotic-resistant bacteria without having to enlarge or label the sample for analysis.
relevant paper information: