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Prostate: The ratio of lymphocytes to monocytes can predict clinically significant prostate cancer

 Last Update: 2021-10-10
 Source: Internet
 Author: User

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prostate secretions

pancreatic cancer detection

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With the extension of people's life span and the popularity of cancer screening, more and more men undergo prostate biopsy when the prostate specific antigen (PSA) is elevated or the digital rectal examination (DRE) is abnormal
.
Although transrectal ultrasound-guided prostate biopsy (TRUS-Bx) is the current reference standard for the detection of prostate cancer, it is related to the over-diagnosis of clinically insignificant prostate cancer and the under-diagnosis of clinically significant prostate cancer.

High morbidity is associated

Inflammation plays a key role in different stages of carcinogenesis and cancer progression
.
Some previous studies have shown that the predictive role of systemic inflammatory markers in clinically significant prostate cancer (CSPCs) is contradictory

Some previous studies have shown that the predictive role of systemic inflammation markers in clinically significant prostate cancer (CSPCs) is contradictory .

Recently, researchers from South Korea have determined the predictive effect of lymphocyte/monocyte ratio (LMR) and eosinophil/lymphocyte ratio (ELR) on CSPC
.

Determined the predictive effect of lymphocyte/monocyte ratio (LMR) and eosinophil /lymphocyte ratio (ELR) on CSPC Determined lymphocyte/monocyte ratio (LMR) and eosinophil/lymphocyte ratio (ELR) Predictive effect on CSPC

The researchers analyzed the clinical and pathological data of 1,740 men, all of whom underwent a 12-core TRUS-Bx examination
.
Calculate LMR and ELR based on the complete blood count before the examination

Comparison of research variables in patients with benign diseases, clinically significant cancers and clinically insignificant cancers

In summary, compared with ELR, LMR has an independent predictive effect
.
The predictive effect of LMR is more meaningful for men with larger prostates

Compared with ELR, LMR has an independent predictive effect

Original source:

Min Chul Cho, Sangjun Yoo, Min Soo Choo et al.

Lymphocyte-to-monocyte ratio is a predictor of clinically significant prostate cancer at prostate biopsy.

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