Progress in gene expression analysis of honeysuckle with different efficacy

Business news on June 12: in recent days, researcher Yu Jun and his team, Key Laboratory of Beijing Institute of genomics, Chinese Academy of Sciences, cooperated with Institute of traditional Chinese medicine, Chinese Academy of traditional Chinese medicine, using the new generation of high-throughput sequencing platform (Illumina's GA platform) sequenced and analyzed the gene expression in three different stages of two honeysuckle varieties (FLJ and rflj) with different efficacy, and the relevant research results were published in BMC genomics Honeysuckle belongs to the honeysuckle family It has a long history as an anti-inflammatory and immune traditional Chinese medicine, and it has the functions of dispersing wind heat, clearing blood toxin and so on But the chemical quality of honeysuckle is not stable, which is not conducive to its quality evaluation Through genome-wide correlation analysis, the researchers not only obtained the transcriptional expression map of honeysuckle at different flowering stages, but also established the related enzyme library In the study, researchers integrated transcriptome and metabolic pathway analysis to reveal whether this system can be used to evaluate the accumulation and quality of active ingredients in honeysuckle According to the evolutionary analysis, the differentiation of specific functions and the differences of gene functions controlling the active components of honeysuckle were revealed The development of the above work has laid an important scientific foundation for the evaluation of the quality of honeysuckle and the evaluation of Chinese herbal medicine efficacy.