Progress has been made in the study of the active ingredients of peppers in Lanzhou Chemical Institute of the Chinese Academy of Sciences

Chinese medicine peppers are Zanthoxylum schinifolium Sieb. the dried, ripe peels of et Zucc, or Zanthoxylum Bungeanum Maxim., belong to the medicinal source and have been cultivated in our country for more than 3,000 years.
the roots, trunks, branches, leaves and fruits of peppers have special uses.
peppers have the effect of astration pain, insecticidal itching, used for abdominal cold pain, vomiting and diarrhea, insect accumulation abdominal pain;
same time, pepper trees belong to the important tree species of mountain ecological afforestation, and the pepper industry is closely linked with ecological construction, return to forest, soil and water conservation, adjustment of rural industrial structure and poverty alleviation and development.
Junli team, a researcher at the Northwest Specialty Plant Resource Chemistry Key Laboratory of Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, used modern separation technology, structural identification technology and drug screening technology to remove peppers (Z. Bungeanum) Screening in dried ripe peels found benzene ethanol acetylcholinesterase inhibitors (Analytical Methods, 2019, 11:4931);
recently, the team isolated and identified Bunsteroid A (see figure), a carbide compound with a carbon skeleton, from Z. Bungeanum Maxim., a 6/6/6/6/5 pentacetonoid natural product containing 34 carbons, which is presumed to be produced by DMAPP and cup oxycodone by methyl dihydrate.
the study provides a scientific basis for the basis of the active substance of peppers and related new drug research.
the study was published in The Journal of Organic Chemistry, Meng Xianhua, an assistant researcher at Lanzhou Chemical Institute, and Chai Sweet, an assistant engineer, were the co-authors of the paper, and Yang Junli was the paper's correspondent.
the results of the study, which was selected as a hot compound by Nature Product Report (DOI:10.1039/d0np90037k).
research work has been funded by the national key research and development plan, the National Natural Science Foundation of China, Gansu Province key research and development plan, the Chinese Academy of Sciences "Western Light" cross-team project, Lanzhou Chemical Institute "135" major breakthrough project.
paper links the new skeleton steroid Bunsteroid A found in peppers