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Hepatitis E Virus (HEV) is one of the leading pathogens of
The clinical diagnosis of hepatitis E mainly relies on diagnostic methods
The study, by semi-quantitative evaluation of the HEV pORF2 antigen in the urine of patients with acute and chronic hepatitis E, found that there was a large amount of pORF2 antigen in the urine of HEV-infected people, and its average level even reached about
Further studies have shown that the pORF2 protein in the urine of patients with hepatitis E is a dimer protein with a monomeric size of 20 kDa, which can identify regions (a.
Urine antigen detection has excellent sensitivity and specificity, while sampling is convenient and non-invasive
The results were published online in Hepatology as a research paper titled "Urine Is a Viral Antigen Reservoir in Hepatitis E Virus Infection"
Paper Link: https://aasldpubs.
(Photo/text National Engineering Research Center for Infectious Disease Diagnostics and Vaccines)