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Invasive growth of cancer cells in the brain makes it difficult to accurately locate the tumor boundary, which is the main reason for the high mortality and high recurrence rate of glioma
.
The acidification of extracellular fluid caused by high levels of glucolysis in cancer cells is a typical feature of almost all solid tumors
Recently, a joint research team of Prof.
Li Cong and Prof.
Mao Ying from our office, Prof.
Zhang Xiaoyong from the Institute of Brain-inspired Intelligence Science and Technology, and Prof.
Yu Jinhua from the School of Information Science and Technology has constructed a class of colloids based on surface-enhanced Raman scattering (SERS) technology.
Proof-of-principle system for tumor surgical navigation
.
The system consists of a self-developed pH-responsive SERS chip, a handheld Raman spectrometer and a Raman spectroscopy deep learning system
Figure 1.
Schematic diagram of the intelligent Raman surgical navigation system
.
The system consists of a self-developed SERS chip, a handheld Raman spectrometer and a deep learning model
The work was published online in the journal Advanced Science under the title "Intelligent SERS Navigation System Guiding Brain Tumor Surgery by Intraoperatively Delineating the Metabolic Acidosis" (Intelligent SERS Navigation System Guiding Brain Tumor Surgery by Intraoperatively Delineating the Metabolic Acidosis)
.
Jin Ziyi, Yue Qi, and Sui An are the co-first authors of the paper
Original link: https://onlinelibrary.
