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The intestinal microbiota is composed of complex microbial communities that are parasitic in the gastrointestinal tract
Antibiotic treatment is the most common way to cause dysbiosis
In this paper, the team revealed that the use of broad-spectrum antibiotics resulted in higher mortality and lower weight gain, and led to significant changes in animal behavior, including reduced exercise and exploratory activities, reduced muscle strength, and internal organs.
This study shows that administration not only directly affects the microflora composition of adolescent mice, but also causes oxidative stress and central nervous system dysfunction
Future research needs to determine the comprehensive mechanism of microbes on brain function
Protective Effects of Probiotics on Cognitive and Motor Functions, Anxiety Level, Visceral Sensitivity, Oxidative Stress and Microbiota in Mice with Antibiotic-Induced Dysbiosis
10.