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Non-small cell lung cancer
Non-small cell lung cancer (NSCLC) accounts for 80%~85% of all lung cancer patients, and small cell lung cancer (SCLC) accounts for 15%~20%.
Radiotherapy is an important means of treatment, including radical radiotherapy, palliative radiotherapy, reduced-symptom radiotherapy and preventive radiotherapy
.
Radical radiotherapy may be considered for early-stage lung cancer that cannot tolerate surgery; Additional radiotherapy
is required for patients whose tumors have not been radically resected or who are locally advanced to intermediate or advanced after surgery.
Radiation therapy for advanced lung cancer is mainly aimed at reducing symptoms, reducing complications, and improving the quality of life of
patients.
For small cell lung cancer, concurrent chemoradiotherapy is the standard of care, and prophylactic whole-brain radiotherapy
is required after curative treatment.
Lymph node grouping and metastasis pathways
Fig.
1-1-1 International Association for the Study of Lung Cancer (IASLC) lymph node atlas
Supraclavicular area: 1.
Lower neck, supraclavicular area, and sternal notch lymph nodes
.
Superior mediastinum: 2R.
right upper paratrachea; 2L.
Upper left
paratrachea; 4R.
Right lower parabronchial; 4L.
Left
lower paratrachea.
Subcarinal zone: 7.
Infracarinal lymph nodes
.
Inferior mediastinum: 8.
paraesophageal lymph nodes (the lower part of the subcarinal lymph nodes); 9.
Pulmonary ligament lymph nodes
.
Hilar/interlobar zone: 10.
Portar lymph nodes, 11.
Interlobar lymph nodes
.
Surrounding area: 12.
Leaf lymph nodes, 13.
Segmental bronchial lymph nodes, 14.
Subsegmental lymph nodes
.
Fig.
1-1-2 Prevascular lymph nodes (3a) and retrotracheal lymph nodes (3p)
Fig.
1-1-3 Aortic lymph nodes:
5.
Active subpulse lymph nodes;
6.
Para-aortic lymph nodes (ascending aorta or phrenic nerve)
Diffusion characteristics
Clinical diagnosis, staging
Imaging tests
Radiation therapy for lung cancer
Radiation therapy techniques for lung cancer
Comprehensive treatment of lung cancer
References:
[ 1 ] CHEN Wanqing, SUN Kexin, ZHENG Rongshou.
Analysis of malignant tumor incidence and mortality by region in China in 2014.
Chinese Journal of Oncology,2018,27(1):1-14.
[ 2 ] Kong FM,Ritter T,Quint DJ,et al.
Consideration of dose limits for organs at risk of thoracic radiotherapy:
atlas for lung,proximal bronchial tree,esophagus,spinal cord,ribs,and brachial plexus.
Int J Radiat
Oncol Biol Phys,2011; 81(5):1442-1457.
[ 3 ] Volterrani L,Mazzei MA,Banchi B,et al.
MSCT multi-criteria: a novel approach in assessment of
mediastinal lymph node metastases in non-small cell lung cancer.
Eur J Radiol,2011; 79(3):459-466.
[ 4 ] Almeida FA,Uzbeck M,Ost D.
Initial evaluation of the nonsmall cell lung cancer patient: diagnosis and
staging.
Curr Opin Pulm Med,2010; 16(4):307-314.
The views expressed in this article only represent the author and are for communication and learning only