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    Home > Medical News > Latest Medical News > Popular science: How effective is the existing new crown vaccine against the Omicron strain

    Popular science: How effective is the existing new crown vaccine against the Omicron strain

    • Last Update: 2022-08-15
    • Source: Internet
    • Author: User
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    Due to the significantly enhanced transmission ability, the Omicron strain quickly replaced Delta and became the main epidemic new coronavirus strain in the wor.
    The Ormicron strain also shows a strong ability of continuous evolution, and has evolved many subtypes so f.
    Can existing COVID-19 vaccines still provide protection against frequently mutated Omicron strains?
     
    Reinforcing needles significantly improve protection
     
    In the weekly epidemic report released by the World Health Organization on the 11th, the conclusions of 23 studies evaluating the protective efficacy of the existing new crown vaccines against the infection of the Omicron strain were summariz.
    The studies came from 10 countries including Brazil, Canada, the Czech Republic, and Denmark, and evaluated marketed vaccines such as Pfizer, Moderna, AstraZeneca, Sinovac and Janss.
    Some of the studies evaluated only the effect of completing the routine vaccination, some only evaluated the effect of a booster dose of the vaccine, and some evaluated the effect of bo.
     
    The results show that, compared with the alpha strain and other four new coronavirus variants classified as "requires attention", the routine vaccination of the new crown vaccine is effective in preventing Omicron strain infection, symptomatic infection and causing severe disea.
    have declin.
    However, it is worth noting that in most studies, the existing vaccines are still highly effective in preventing severe disease caused by Omicron; in all relevant studies, a booster dose of the vaccine significantly improved the vaccine's effectiveness in preventing Omicr.
    The effects of infection, symptomatic infection and severe illne.
     
    In terms of the effect of booster shots, the 36 related evaluations involving multiple vaccine booster shots involved in the study showed that within 14 days to 3 months after receiving a dose of booster shots, the effect of preventing severe illness caused by Omicron was significantly improv.
    There are 34 assessments showing that the effective rate of preventing severe illness is higher than 70% within 14 days to 3 months after a booster dose is giv.
    Of the 20 longer-term efficacy evaluations of mRNA vaccine booster shots, 18 evaluations showed that within 3 to 6 months after a dose of mRNA vaccine booster shot, the effective rate of preventing severe illness was more than 7
     
    The WHO pointed out in its weekly report that in the future, it is necessary to evaluate the effect of vaccination booster shots beyond 6 months to understand the protective efficacy of the vaccine over a longer period of ti.
     
    Be wary of new subtypes of immune escape
     
    What needs to be vigilant is that the Omicron strain has recently evolved some new subtypes, including .
    4, .
    5 reported by South African researchers, and .
    11 that is rapidly spreading in the United Stat.

    The website of the American "Science" magazine published an article on the 10th that, similar to the earlier Omicron subtypes, the three subtypes .

    4, .

    5 and .

    11 are highly resistant to vaccination against the new crown or previous infection with the new cro.

    The antibodies produced show the ability to escape, but in most cases immunity acquired through vaccination or natural infection still prevents severe diseas.

     
    This article describes two preprint studies published recent.

    One was published on the Archives of Medical Papers Network by researchers at institutions including the African Institute of Health Research in South Afric.

    Studies have shown that .

    4 and .

    5 can evade immunity and lead to symptomatic infection in some people who have been previously infected with the Omicron subtype strain .

    1 and thus acquired immunity, especially in the futu.

    This phenomenon is more pronounced in the vaccinated populati.

    This suggests that .

    4 and .

    5 have the potential to spark a new "wave of infectio.

     
    Another study, published on the "Research Square" website by a team led by researchers from Peking University's Center for Biomedical Frontier Innovation, said that compared with the .

    2 subtype, .

    4, .

    5 and .

    11 The plasma of three-dose vaccinated patients showed stronger antibody neutralization escape ability, especially the plasma of vaccinated .

    1 infection recovered patients showed significant neutralization escape abili.

     
    The researchers also analyzed the immune escape mechanisms of the three new subtypes described above based on their key mutatio.

    The spike receptor binding domains of .

    4, .

    5 and .

    11 all carry the L452 mutati.

    The L452 mutation has previously appeared in the delta strain, but the early omicron subtype .

    1 does not contain the L452 mutati.

     
    The researchers believe that multiple Omicron subtypes that have emerged recently carry the L452 mutation, which may be a response of the new coronavirus to the high level of population immunity caused by the "wave of infection" of Omicr.

    Studies have shown that Omicron has been able to evolve certain mutations that specifically evade the humoral immunity elicited by .

    1 infecti.

     
    Although it is not known what new coronavirus variants will emerge in the future, it is almost certain that they will be increasingly capable of immune evasion, Christian Anderson, a virologist at the Scripps Research Institute in the United States, told Science magazi.

    "We need to focus on expanding our immunity" in future vaccine development effor.

    Due to the significantly enhanced transmission ability, the Omicron strain quickly replaced Delta and became the main epidemic new coronavirus strain in the wor.

    The Ormicron strain also shows a strong ability of continuous evolution, and has evolved many subtypes so f.

    Can existing COVID-19 vaccines still provide protection against frequently mutated Omicron strains?
     
    Reinforcing needles significantly improve protection
     
    In the weekly epidemic report released by the World Health Organization on the 11th, the conclusions of 23 studies evaluating the protective efficacy of the existing new crown vaccines against the infection of the Omicron strain were summariz.

    The studies came from 10 countries including Brazil, Canada, the Czech Republic, and Denmark, and evaluated marketed vaccines such as Pfizer, Moderna, AstraZeneca, Sinovac and Janss.

    Some of the studies evaluated only the effect of completing the routine vaccination, some only evaluated the effect of a booster dose of the vaccine, and some evaluated the effect of bo.

     
      The results show that, compared with the alpha strain and other four new coronavirus variants classified as "requires attention", the routine vaccination of the new crown vaccine is effective in preventing Omicron strain infection, symptomatic infection and causing severe disea.

    have declin.

    However, it is worth noting that in most studies, the existing vaccines are still highly effective in preventing severe disease caused by Omicron; in all relevant studies, a booster dose of the vaccine significantly improved the vaccine's effectiveness in preventing Omicr.

    The effects of infection, symptomatic infection and severe illne.

     
      In terms of the effect of booster shots, the 36 related evaluations involving multiple vaccine booster shots involved in the study showed that within 14 days to 3 months after receiving a dose of booster shots, the effect of preventing severe illness caused by Omicron was significantly improv.

    There are 34 assessments showing that the effective rate of preventing severe illness is higher than 70% within 14 days to 3 months after a booster dose is giv.

    Of the 20 longer-term efficacy evaluations of mRNA vaccine booster shots, 18 evaluations showed that within 3 to 6 months after a dose of mRNA vaccine booster shot, the effective rate of preventing severe illness was more than 7
     
      The WHO pointed out in its weekly report that in the future, it is necessary to evaluate the effect of vaccination booster shots beyond 6 months to understand the protective efficacy of the vaccine over a longer period of ti.

     
      Be wary of new subtypes of immune escape
     
      What needs to be vigilant is that the Omicron strain has recently evolved some new subtypes, including .

    4, .

    5 reported by South African researchers, and .

    11 that is rapidly spreading in the United Stat.

    The website of the American "Science" magazine published an article on the 10th that, similar to the earlier Omicron subtypes, the three subtypes .

    4, .

    5 and .

    11 are highly resistant to vaccination against the new crown or previous infection with the new cro.

    The antibodies produced show the ability to escape, but in most cases immunity acquired through vaccination or natural infection still prevents severe diseas.

     
      This article describes two preprint studies published recent.

    One was published on the Archives of Medical Papers Network by researchers at institutions including the African Institute of Health Research in South Afric.

    Studies have shown that .

    4 and .

    5 can evade immunity and lead to symptomatic infection in some people who have been previously infected with the Omicron subtype strain .

    1 and thus acquired immunity, especially in the futu.

    This phenomenon is more pronounced in the vaccinated populati.

    This suggests that .

    4 and .

    5 have the potential to spark a new "wave of infectio.

     
      Another study, published on the "Research Square" website by a team led by researchers from Peking University's Center for Biomedical Frontier Innovation, said that compared with the .

    2 subtype, .

    4, .

    5 and .

    11 The plasma of three-dose vaccinated patients showed stronger antibody neutralization escape ability, especially the plasma of vaccinated .

    1 infection recovered patients showed significant neutralization escape abili.

     
      The researchers also analyzed the immune escape mechanisms of the three new subtypes described above based on their key mutatio.

    The spike receptor binding domains of .

    4, .

    5 and .

    11 all carry the L452 mutati.

    The L452 mutation has previously appeared in the delta strain, but the early omicron subtype .

    1 does not contain the L452 mutati.

     
      The researchers believe that multiple Omicron subtypes that have emerged recently carry the L452 mutation, which may be a response of the new coronavirus to the high level of population immunity caused by the "wave of infection" of Omicr.

    Studies have shown that Omicron has been able to evolve certain mutations that specifically evade the humoral immunity elicited by .

    1 infecti.

     
      Although it is not known what new coronavirus variants will emerge in the future, it is almost certain that they will be increasingly capable of immune evasion, Christian Anderson, a virologist at the Scripps Research Institute in the United States, told Science magazi.

    "We need to focus on expanding our immunity" in future vaccine development effor.

      Due to the significantly enhanced transmission ability, the Omicron strain quickly replaced Delta and became the main epidemic new coronavirus strain in the wor.

    The Ormicron strain also shows a strong ability of continuous evolution, and has evolved many subtypes so f.

    Can existing COVID-19 vaccines still provide protection against frequently mutated Omicron strains?
     
      Reinforcing needles significantly improve protection
      Reinforcing needles significantly improve protection
     
      In the weekly epidemic report released by the World Health Organization on the 11th, the conclusions of 23 studies evaluating the protective efficacy of the existing new crown vaccines against the infection of the Omicron strain were summariz.

    The studies came from 10 countries including Brazil, Canada, the Czech Republic, and Denmark, and evaluated marketed vaccines such as Pfizer, Moderna, AstraZeneca, Sinovac and Janss.

    Some of the studies evaluated only the effect of completing the routine vaccination, some only evaluated the effect of a booster dose of the vaccine, and some evaluated the effect of bo.

     
      The results show that, compared with the alpha strain and other four new coronavirus variants classified as "requires attention", the routine vaccination of the new crown vaccine is effective in preventing Omicron strain infection, symptomatic infection and causing severe disea.

    have declin.

    However, it is worth noting that in most studies, the existing vaccines are still highly effective in preventing severe disease caused by Omicron; in all relevant studies, a booster dose of the vaccine significantly improved the vaccine's effectiveness in preventing Omicr.

    The effects of infection, symptomatic infection and severe illne.

     
      In terms of the effect of booster shots, the 36 related evaluations involving multiple vaccine booster shots involved in the study showed that within 14 days to 3 months after receiving a dose of booster shots, the effect of preventing severe illness caused by Omicron was significantly improv.

    There are 34 assessments showing that the effective rate of preventing severe illness is higher than 70% within 14 days to 3 months after a booster dose is giv.

    Of the 20 longer-term efficacy evaluations of mRNA vaccine booster shots, 18 evaluations showed that within 3 to 6 months after a dose of mRNA vaccine booster shot, the effective rate of preventing severe illness was more than 7
     
      The WHO pointed out in its weekly report that in the future, it is necessary to evaluate the effect of vaccination booster shots beyond 6 months to understand the protective efficacy of the vaccine over a longer period of ti.

     
      Be wary of new subtypes of immune escape
      Be wary of new subtypes of immune escape
     
      What needs to be vigilant is that the Omicron strain has recently evolved some new subtypes, including .

    4, .

    5 reported by South African researchers, and .

    11 that is rapidly spreading in the United Stat.

    The website of the American "Science" magazine published an article on the 10th that, similar to the earlier Omicron subtypes, the three subtypes .

    4, .

    5 and .

    11 are highly resistant to vaccination against the new crown or previous infection with the new cro.

    The antibodies produced show the ability to escape, but in most cases immunity acquired through vaccination or natural infection still prevents severe diseas.

    disease disease disease
     
      This article describes two preprint studies published recent.

    One was published on the Archives of Medical Papers Network by researchers at institutions including the African Institute of Health Research in South Afric.

    Studies have shown that .

    4 and .

    5 can evade immunity and lead to symptomatic infection in some people who have been previously infected with the Omicron subtype strain .

    1 and thus acquired immunity, especially in the futu.

    This phenomenon is more pronounced in the vaccinated populati.

    This suggests that .

    4 and .

    5 have the potential to spark a new "wave of infectio.

    healthy healthy healthy
     
      Another study, published on the "Research Square" website by a team led by researchers from Peking University's Center for Biomedical Frontier Innovation, said that compared with the .

    2 subtype, .

    4, .

    5 and .

    11 The plasma of three-dose vaccinated patients showed stronger antibody neutralization escape ability, especially the plasma of vaccinated .

    1 infection recovered patients showed significant neutralization escape abili.

     
      The researchers also analyzed the immune escape mechanisms of the three new subtypes described above based on their key mutatio.

    The spike receptor binding domains of .

    4, .

    5 and .

    11 all carry the L452 mutati.

    The L452 mutation has previously appeared in the delta strain, but the early omicron subtype .

    1 does not contain the L452 mutati.

     
      The researchers believe that multiple Omicron subtypes that have emerged recently carry the L452 mutation, which may be a response of the new coronavirus to the high level of population immunity caused by the "wave of infection" of Omicr.

    Studies have shown that Omicron has been able to evolve certain mutations that specifically evade the humoral immunity elicited by .

    1 infecti.

     
      Although it is not known what new coronavirus variants will emerge in the future, it is almost certain that they will be increasingly capable of immune evasion, Christian Anderson, a virologist at the Scripps Research Institute in the United States, told Science magazi.

    "We need to focus on expanding our immunity" in future vaccine development effor.

    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

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