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    Home > Biochemistry News > Biotechnology News > PNAS: Breaking the Defenses of Pancreatic Tumors

    PNAS: Breaking the Defenses of Pancreatic Tumors

    • Last Update: 2022-03-03
    • Source: Internet
    • Author: User
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    T cells patrol the body in search of cancer and pathogens


    The scientists used gene editing to turn off the production of KRT19 or TGM2 in mouse pancreatic tumors


    Why does this layer of protein repel T cells in the tumor? "It's a bit counterintuitive because CXCL12 is a chemokine (chemoattractant) that attracts immune cells," Wang said


    The study was published in the Proceedings of the National Academies of Sciences


    Journal Reference :

    1. Zhikai Wang, Philip Moresco, Ran Yan, Jiayun Li, Ya Gao, Daniele Biasci, Min Yao, Jordan Pearson, Jaclyn F.



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