PLoS One: safe and effective birth control pill for men! The age of male contraception is coming!

April 29, 2018 / Biovalley / a new study published in PLoS One recently found that a compound called ep055 can bind to sperm protein to significantly reduce sperm motility without affecting hormone levels, which makes ep055 possible as a male contraceptive without side effects Photo source: © areeya_ann / fotolia "simply put, this compound blocks the ability of sperm to swim, thereby significantly reducing the rate of conception." Michael o'rand, PhD, research lead author, retired professor of cell biology and physiology, University of North Carolina, Chapel Hill School of medicine, CEO and chairman of Eppin Pharma, Inc "This makes ep055 a potential non hormonal male contraceptive candidate." At present, condom and surgical vasectomy are safe contraceptive methods for men At the same time, there are also some hormone drugs in clinical trials These drugs can target groups to prevent sperm production, but they will affect men's natural hormones, just like women's contraceptives affect women's hormones In this study, after 34 hours of intravenous injection of high dose ep055 in male rhesus monkeys, Dr o'rand and his colleagues found that these rhesus monkeys did not have sperm that could move normally, and no side effects were found "After 18 days, the reproductive capacity of all rhesus monkeys was completely restored, indicating that the effect of ep055 was completely reversible." Dr Mary Zelinski, co-author of the study, said Dr o'rand and Dr Zelinski say more research is needed before ep055 can be used in humans They and their team will begin testing the tablet form of the drug, eventually conducting clinical trials to study its contraceptive effect on men (bio Com) reference: Michael g o'rand, Katherine g Hamil, Tiffany adevai, Mary Zelinski Occupation of sperm mobility in male macaques with ep055, a potential non domestic male contract PLoS One, 2018; 13 (4): e0195953 doi: 10.1371/journal.pone.0195953