PLoS neg trop dis: an effective method for the treatment of Taenia solium

January 18, 2020 / BIOON / -- Taenia solium, also known as pork tapeworm, is a worldwide parasite that causes serious diseases, especially in poor communities lacking adequate and clean pork products Now, researchers have compared the efficacy and adverse effects of three chemotherapy treatments on Taenia solium The results are published in the latest PLoS novel clinical disease Adult Taenia solium can cause intestinal infection in pigs When people eat raw, infected pork that contains Trypanosoma suis larvae, they may also become infected This infection can cause abnormal symptoms in the muscles and central nervous system, including seizures In the new study, Michelle Haby of the University of Sonora in Mexico and colleagues reviewed existing literature on three existing insecticides that show efficacy in treating the infectious disease The drugs are albendazole (ALB), praziquantel (PZQ) and nicotinamide (NICL) Meta analysis showed that a single dose of PZQ 10 mg / kg could cure 99.5% of herpes zoster The cure rate of 400 mg ALB was 96.4% and that of NiCl 2G was 84.3% The poor effect was PZQ 5mg / kg, the cure rate was 89.0%, ALB 400mg, the cure rate was 52.0% Most studies reported no or only mild and transient side effects after administration Future studies on efficacy should focus on high-quality, randomized controlled trials of three different drugs and different doses, compared to placebo and head to head trials, the researchers said Information source: efficient of drugs against pork tapeworm original source: Michelle M Haby, Leopoldo A Sosa Leon, Ana Lucia ñ EZ, Ruben Santiago Nicholls, Ludovic reveiz, Meritxell donadeu Systematic review of the effectiveness of selected drugs for preventive chemotherapy for taneia solid taeniasis PLoS centralized tropical diseases, 2020; 14 (1): e0007873 DOI: 10.1371/journal.pntd.0007873