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    Home > Active Ingredient News > Anesthesia Topics > Plast Reconstr Surg: Chronic neuralgia after burns, an anatomical method and development and validation of a model for predicting patient risk

    Plast Reconstr Surg: Chronic neuralgia after burns, an anatomical method and development and validation of a model for predicting patient risk

    • Last Update: 2021-11-12
    • Source: Internet
    • Author: User
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    According to reports, the prevalence of burn-related nerve pain ranges from 6% to 82%
    .


    Burn doctors have a comprehensive understanding of the appropriate medical treatment of acute pain in burn wounds, but the chronic manifestations of nerve pain after burns are unclear


    Previous reports on the risk factors for burn-related neuralgia that are not related to anatomical location include age over 20 years old, total body surface area burn percentage of more than 20%, whole body burns, critical illness, electrical injury, and alcoholism
    .

    The location of the burn can determine whether there is a risk of burn-related neuralgia
    .


    If the risk of burn-related neuralgia in burn patients can be predicted, elective medical or surgical treatment in the early acute phase of burn treatment may improve the patient’s prognosis


    The purpose of this study is to determine the characteristics of burn patients involving different anatomical parts of the body to determine the anatomical specific risk factors, and then develop and verify a model based on mathematical equations, which mainly divides patients into 11 anatomical burn parts for comparison (ie Hands, forearms, upper arms, chest/abdomen, back, buttocks/genitals, thighs, calves, feet, face/head, neck) compare each anatomical burn site of patients with and without burn-related neuralgia
    .

    Figure 1 Screenshot of the source of the article

    The study conducted a retrospective analysis and model development of 1,862 adults admitted to the burn center from 2014 to 2019
    .


    Among them, 113 patients had burn-related neuralgia


    Figure 2 11 anatomical positions

    The results showed that the prevalence of burn-related nerve pain was similar in the development (6.
    1%) and validation (5.
    4%) cohorts
    .

    Eight variables are included in the final equation
    .


    The formula is as follows:

    Burn-related nerve pain risk score = −6.
    3 + 0.
    02 (age) + 1.
    77 (smoking) + 1.
    04 (drug abuse) + 0.
    67 (alcohol abuse) + 0.
    84 (upper arm burn) + 1.
    28 (thigh burn) + 0.
    21 (number of burn operations) +0.
    01 (Hospitalization time)
    .


    Predictive probability of burn-related neuralgia=1− 1/[1+exp (risk score of burn-related neuralgia)]

    This can be used for a 6-month burn-related nerve pain risk score
    .

    In addition, as the number of risk factors increases, the likelihood of pain increases
    .

     

    In the end, the researchers identified the risk factors for burn-related nerve pain in 11 anatomical locations and developed related models
    .


    The model accurately predicted the risk of burn-related neuralgia in patients at 6 months


     

    Original article:

    Klifto Kevin M, Yesantharao Pooja S, Lifchez Scott D et al.


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