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Sodium picco sulfate, about the introduction of sodium piccoa sulfate many people do not know, now let's take a look at it! 1.
Sodium picco sulfate is a laxative developed by De Angeli Company in Italy, which is a special laxative with a special mode of action, which has a mild laxative effect
on the direct action of the large intestinal mucosa.
2.
It can not only be used for various forms of constipation, but also can eliminate the pain of defecation caused by hemorrhoids or fissures, and is also used for defecation difficulties
.
Studies have shown that sodium pic sulfate has no gastrointestinal reaction, and is produced by the hydrolytic enzyme of the colonic flora to produce diphenols to play a laxative effect, of which pico sulfate shows a good laxative effect
.
The site of action of sodium piccosulfate is the colon, and the active ingredient diphenols are produced after the enzymatic hydrolysis produced by the colonic flora, which can directly stimulate the intestinal mucosa, promote intestinal peristalsis and inhibit the absorption of water in the intestine, showing the effect
of diarrhea.
Excretion in the urine shows that sodium piccosulfate is almost no absorption in the gastrointestinal tract, has little systemic effect, and the efficacy is independent
of the plasma concentration of the active ingredient.
This concludes this article, I hope it will be helpful to
you.
