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Phase III study of CXCR4 inhibitor fails, Fosun Pharma has China rights

 Last Update: 2021-08-29
 Source: Internet
 Author: User

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On June 28, PolyphorAG announced that the global phase III study (FORTRESS) of Balixafortide (POL6326) combined with Eribulin in the treatment of HER2-negative, locally recurring or metastatic breast cancer did not meet the common primary endpoint

Polyphor product pipeline (Source: Polyphor AG)

Balixafortide is an effective and highly selective CXCR4 inhibitor developed based on Polyphor AG's macrocyclic technology platform

Polyphor Dahuan Technology Platform (Source: Polyphor AG)

The FORTRESS study (POL6326-009) is a randomized, open-label, positive-controlled, international multicenter phase III study, which aims to evaluate intravenous balixafortide combined with eribulin versus eribulin monotherapy in the treatment of HER2-negative local Efficacy, safety and tolerability of recurrent or metastatic breast cancer

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