Pharmaceutical-grade crosslinked povidone uses disintegrators and fillers

Pharmaceutical grade cross-linked povidone use disintegrant and filler generic name: cross-linked povidone, Crospovidone, Crospovidonum Chemical name: cross-linked polyvinyl pyrrolidone, 1-vinyl-2-pyrrolidone homopolymer, 1-etheyl-2-pyrolidione homopolymerCAS No: 9003-39-8 This product is an insoluble water-soluble homopolymer
synthesized by N-ethylene-2-pyrrolidone 。 The molecular formula is (C6H9NO)n, where n represents the average number of
1-vinyl-2-pyrrolidone links.
According to the calculation of anhydrous, the nitrogen content (N) should be 11.
0%~12.
8%.

【Properties】This product is white or off-white powder
.
This product is insoluble
in water, ethanol or three.
【Identification】(1) take 1g of this product, add 10ml of water to shake to disperse into a suspension, add 0.
1ml of iodine test solution, shake for 30 seconds, add 1ml of starch indicator solution, shake, there should be no blue color
.
(2) The infrared light absorption spectrum of this product should be consistent with the spectrum of the reference substance (General rule 0402).

Cross-linked polyethylene is a thermosetting plastic with a network structure, which has outstanding wear resistance, solvent resistance, dimensional stability, stress crack resistance, anti-aging and weather resistance, non-toxic, tasteless, non-absorbent; Good low temperature flexibility, excellent heat resistance, softening point up to 200 °C, can be used for a long time at 140 °C; Impact strength, tensile strength, creep resistance and rigidity are better than HDPE, and the elastic modulus is 5 times higher than HDPE.
Some have electrical insulation, low temperature resistance, chemical stability and radiation resistance
.
The film has moderate transparency and sufficient water vapor permeability
.
After heating, blowing (stretching), cooling and shaping, cross-linked polyethylene can naturally return to its original shape and size (that is, shape memory)
when reheated above the crystallization temperature.
Cross-linked polyethylene commonly used in industry includes radiation cross-linked polyethylene, peroxide cross-linked polyethylene and silane cross-linked polyethylene
.
Radiation cross-linked polyethylene film performance organic peroxide cross-linked polyethylene structure and thermoplastics, thermosetting resins and vulcanized rubber are different, it has a body structure but not completely cross-linked, the cross-linking area is very small, not like vulcanized rubber has a large cross-networking, so in performance it has the characteristics of three at the same time, that is, it has both thermoplasticity, hardness, good solvent resistance, high elasticity and excellent low temperature
resistance 。 Whether it is high-density polyethylene or low-density polyethylene, its tensile strength, heat resistance, aging and weather resistance, dimensional stability, stress crack resistance, wear resistance and solvent resistance are improved after crosslinking, and the creep resistance is excellent
.
The softening point of cross-linked polyethylene can reach 200 °C, and the heat resistance can reach 140 °C
.
In addition, it has electrical insulation, low temperature resistance, and radiation resistance
.
Properties of
peroxide crosslinked polyethylene.
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