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Pfizer's JAK inhibitor secures fifth indication for active ankylosing spondylitis

 Last Update: 2022-02-24
 Source: Internet
 Author: User

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On December 14, 2021, Pfizer announced that the U.

AS is a chronic inflammatory disease with symptoms usually occurring before the age of 30

Tofacitinib is a JAK inhibitor developed by Pfizer, which can effectively inhibit the activity of JAK1 and JAK3 and block the signaling of various inflammatory cytokines

The approval is based on positive data from a multicenter, randomized, double-blind, placebo-controlled Phase 3 clinical trial

Note: The original text has been deleted

References:

[1] US FDA Approves Pfizer's XELJANZ® (tofacitinib) for the Treatment of Active Ankylosing Spondylitis.

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