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Lower blood levels of high-density lipoprotein (high-density cholesterol) and higher triglycerides, measured as early as age 35, are associated with higher rates of AD decades later in life, according to the latest study
The researchers believe that although high LDL has been consistently associated with AD risk in many previous studies, the link between HDL and AD is inconclusive, likely because most studies were conducted in people 55 and older of
The data for the study came from participants in the Framingham Heart Study, who were checked about every four years for most of their adult life
The researchers found that low HDL (good cholesterol) predicted AD in early (35-50) and mid-life (51-60) adults, while high blood sugar (a precursor to diabetes) in mid-term also AD can be predicted
According to the researchers, careful management of these factors from early adulthood can reduce a person's risk of cardiovascular disease, diabetes, and Alzheimer's
This is a multigenerational, community-based, prospective health study that began in 1948, allowing us to link Alzheimer's disease with risk factors for heart disease and diabetes more than most other cognitive decline and dementia Symptoms were studied much earlier
Alzheimer's & Dementia
Midlife lipid and glucose levels are associated with Alzheimer's disease