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PD-1 monoantivo combined with beret meth and chemotherapy: significantly improved progression-free survival in patients with non-small cell lung cancer.

 Last Update: 2020-08-23
 Source: Internet
 Author: User

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Japan's Ono Pharmaceutical Co., Ltd. announced that PD-1 monoantiphone Opdivo (nivolumab) combined anti-VEGF (vascular endoder growth factor) mono-bevacizumab and chemotherapy, treatment of non-small cell lung cancer Phase III clinical success.
Image source: Picture Source: In the ONO-4538-52/TASUKI-52 study, the Opdivo combination group (n s 275) was compared with a simple placebo combined with beva monotherapy and chemotherapy (placebo group: n s 275) in patients with IIIB/IV stage or recurrent non-squamous non-small cell lung cancer who were not suitable for radiotherapy.
analysis showed that the Opdivo group showed significant statistical improvement in the main endpoints of progression-free survival (PFS) compared to the placebo group, and no new safety issues were identified.
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