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Patients with acute oligoarthritis diagnosed with gout, a more accurate ultrasound scan program is here!

 Last Update: 2022-10-03
 Source: Internet
 Author: User

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Clinical information, 1s reach

▎Clinical Questions: What is the most accurate ultrasound (US) scan protocol for diagout and calcium pyrophosphate deposition disease (CPPD) in patients with unexplained acute mono/oligoarthritis?
Screenshot ▎ Study protocol: Patients with acute mono/oligoarthritis [161 subjects (32 patients with gout, 30 patients with CPPD, and 99 controls] were included, and joint aspiration
was performed on the joints with the most obvious symptoms (target joints).

The specificities for the diagnosis of gout and CPPD in US were (0.
92-0.
96) and (0.
90-0.
97), respectively, and the sensitivity was 0.
73 to 0.
85 (double profile sign and tophi, respectively), and 0.
60 to 0.
90 (hyalurony and fibrocartilage deposition, respectively).

The US assessment of bilateral joints (gout: knee, 1st metatarsophalange, CPPD: knee, wrist) + target joint has excellent diagnostic sensitivity (gout: 0.
91, CPPD: 0.
93) and specificity (gout: 0.
91, CPPD: 0.
89
).

This targeted US scanning protocol yielded higher diagnostic accuracy (gout, AUC: 0.
91 vs AUC: 0.
84, p=0.
03; CPPD, AUC: 0.
93 vs AUC: 0.
84, p=0.
04)
compared with the US assessment of the target joint.

Unless the target joint of gout is the knee joint or the 1st metatarsophalangeal joint and the target joint of CPPD is the case of the knee or wrist joint
.

▎Conclusion and Outlook: Targeted US scanning protocol for bilateral joints + target joints (unless it is knee, 1st metatarsophalange, or wrist joint) has good accuracy in diagnosing crystalline arthritis in patients with acute mono/oligoarthritis (>90%)
.

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