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▎Osteoarthritis, edited by WuXi AppTec's content team, is one of the many types of arthritis.
In fact, inflammation is not only manifested in the joints, but also related to the health of other systems
.
A recent study published in Arthritis Care & Research found that patients with osteoarthritis have an increased risk of Parkinson's disease
.
Image source: In the 123RF study, the research team included 33360 50-64-year-old osteoarthritis patients (experimental group) and 33360 age- and gender-matched people without osteoarthritis (control group)
.
Then use various methods to calculate and analyze the relationship between osteoarthritis and Parkinson's disease
.
In the osteoarthritis group, the average follow-up time was 7.
74 years, and the control group had an average follow-up time of 8.
67 years.
The former had 256 patients with Parkinson’s disease, and the latter had 205 patients with Parkinson’s disease
.
The researchers found that compared with the control group, patients with osteoarthritis had a 41% higher probability of developing Parkinson's disease (adjusted hazard ratio 1.
41; P=0.
0004)
.
Among them, patients with knee or hip arthritis have a higher risk of Parkinson's disease than those with non-knee and non-coxarthritis or patients with unclassified osteoarthritis
.
And women have a significantly higher risk of Parkinson's disease than men
.
In patients with osteoarthritis, there are also more complications such as hypertension, coronary heart disease, diabetes, chronic obstructive pulmonary disease, and gout
.
However, although patients with osteoarthritis have a significantly higher risk of Parkinson’s disease, there is no significant difference in all-cause mortality
.
Image source: 123RF According to the researcher’s description: “We noticed increased levels of pro-inflammatory cytokines in patients with osteoarthritis, such as interleukin-6 and tumor necrosis factor alpha, which not only decompose cartilage in bones and joints, but also It exacerbates neuroinflammation and activates microglia
.
"Of course, a single study is not enough to test whether there is a relationship between the two diseases, and the study also has some potential limitations, such as failing to consider the effects of smoking and drinking.
etc.
affect the outcome
.
But at least, we can adjust our diet and life>
.
Image source: What should I pay attention to when 123RF has osteoarthritis? There is no cure for osteoarthritis, so pain and symptom management is particularly important, and diet may help relieve symptoms.
The association of UK Dietitians has the following recommendations: 1.
Maintain a healthy weight.
Obesity or overweight can increase the pressure on the joints; on the other hand, excess fat can cause inflammation, which can aggravate the symptoms
.
Evidence shows that weight loss can reduce pain and improve physical function and mobility
.
For people who are overweight or obese, a 10% weight loss will bring good benefits
.
Osteoarthritis is associated with type 2 diabetes and cardiovascular disease; therefore weight loss can also help prevent or manage these diseases
.
It is recommended to control the BMI between 18.
5~24 kg/m²; the waist circumference of men should be controlled within 90cm, and the waist circumference of women should be controlled within 85cm
.
You can combine diet with exercise, because physical activity can help inhibit neurodegeneration and protect neurons
.
Image source: 123RF 2: Eat anti-inflammatory fats The long-chain omega-3 polyunsaturated fatty acids found in oily fish have anti-inflammatory properties and are likely to be beneficial to osteoarthritis
.
It is recommended to eat at least two servings of oily fish a week, such as sardines, mackerel, and salmon
.
If you cannot consume deep-sea fish, the British Dietitians Association recommends that you consider taking fish oil capsules every day to provide 450mg of EPA+DHA
.
Although strictly speaking this is not enough to fight inflammation, studies have shown that it can improve the pain of patients with knee arthritis
.
Omega-6 polyunsaturated fatty acids and saturated fatty acids have certain pro-inflammatory properties and may worsen symptoms.
Therefore, it is recommended to eat less sunflower oil, corn oil, lard and other animal fats
.
Eat fats rich in monounsaturated fatty acids, such as rapeseed oil, olive oil, and camellia oil
.
Three: Vitamin D supplementation.
Vitamin D is essential for bone and cartilage health
.
Although we can get some vitamin D from our diet, sunlight is the main source of it (subcutaneous 7-dehydrocholesterol is the provitamin D3, which can produce vitamin D3 when exposed to ultraviolet light)
.
Studies have shown that vitamin D may have a positive effect on muscle strength, balance and weight management
.
The vitamin D we get daily is far from enough, so the British Dietitian Association recommends taking vitamin D supplements (10-25 micrograms) daily, especially in winter
.
Source: 123RF four: eat antioxidant vitamins antioxidant vitamins may reduce the occurrence of osteoarthritis oxidative stress, such as vitamin A, C and E
.
Although the evidence for the role of these vitamins in osteoarthritis is weak, they can be used as part of a healthy and balanced diet
.
The rich sources of vitamin A are: carrots, sweet potatoes, liver, etc.
The recommended intake (RNI) is 600-700 micrograms of retinol equivalent/day
.
Foods with rich sources of vitamin C include: citrus fruits, green peppers and red peppers, etc.
RNI: 40 mg/day
.
Foods with rich sources of vitamin E include: whole-wheat grains, nuts and seeds, with a safe intake of 3 to 4 mg/day
.
Foods with rich sources of vitamin D include: oily fish, egg yolks and certain nutrient-fortified foods, RNI: 10 micrograms/day
.
Foods with rich sources of vitamin K include spinach, lettuce, broccoli and Brussels sprouts.
The safe intake is 1 microgram per kilogram of body weight per day
.
In addition, it is recommended to eat 30g of nuts a day, 25g of soy protein, such as tofu, soy milk, soybeans / soybean and so on
.
Recommended reading Is Joint Pain Is Gout? These types of arthritis may also cause more than 3 million Parkinson's disease patients in China: not just "shaking hands".
What is a tumor? What is cancer? What's the difference? This article will take you to understand that the intestines are healthy without constipation? Make the "second brain" healthier and don't ignore it! The American Heart Association publishes that 80% of re-strokes can be prevented, the key is to do these reference materials [1] Shih-Hao Feng, Hung-Jui Chuang, Kuo-Cheng Yeh, Shin-Liang Pan (2021).
Osteoarthritis is associated with an increased risk of Parkinson's disease: A population-based, longitudinal follow-up study.
Arthritis Care & Research.
[2] Osteoarthritis: A Link With Parkinson's?.
Retrieved June 9, 2021, from https:// com/rheumatology/arthritis/92998[3] Osteoarthritis and diet: Food Fact Sheet.
Retrieved June 10, 2021, from https:// Healthy Eating for Knee Osteoarthritis.
Retrieved December 04, 2020, from https:// Note: This article aims to introduce the progress of medical and health research, not a treatment plan recommendation
.
If you need guidance on the treatment plan, please go to a regular hospital for treatment
.
In fact, inflammation is not only manifested in the joints, but also related to the health of other systems
.
A recent study published in Arthritis Care & Research found that patients with osteoarthritis have an increased risk of Parkinson's disease
.
Image source: In the 123RF study, the research team included 33360 50-64-year-old osteoarthritis patients (experimental group) and 33360 age- and gender-matched people without osteoarthritis (control group)
.
Then use various methods to calculate and analyze the relationship between osteoarthritis and Parkinson's disease
.
In the osteoarthritis group, the average follow-up time was 7.
74 years, and the control group had an average follow-up time of 8.
67 years.
The former had 256 patients with Parkinson’s disease, and the latter had 205 patients with Parkinson’s disease
.
The researchers found that compared with the control group, patients with osteoarthritis had a 41% higher probability of developing Parkinson's disease (adjusted hazard ratio 1.
41; P=0.
0004)
.
Among them, patients with knee or hip arthritis have a higher risk of Parkinson's disease than those with non-knee and non-coxarthritis or patients with unclassified osteoarthritis
.
And women have a significantly higher risk of Parkinson's disease than men
.
In patients with osteoarthritis, there are also more complications such as hypertension, coronary heart disease, diabetes, chronic obstructive pulmonary disease, and gout
.
However, although patients with osteoarthritis have a significantly higher risk of Parkinson’s disease, there is no significant difference in all-cause mortality
.
Image source: 123RF According to the researcher’s description: “We noticed increased levels of pro-inflammatory cytokines in patients with osteoarthritis, such as interleukin-6 and tumor necrosis factor alpha, which not only decompose cartilage in bones and joints, but also It exacerbates neuroinflammation and activates microglia
.
"Of course, a single study is not enough to test whether there is a relationship between the two diseases, and the study also has some potential limitations, such as failing to consider the effects of smoking and drinking.
etc.
affect the outcome
.
But at least, we can adjust our diet and life>
.
Image source: What should I pay attention to when 123RF has osteoarthritis? There is no cure for osteoarthritis, so pain and symptom management is particularly important, and diet may help relieve symptoms.
The association of UK Dietitians has the following recommendations: 1.
Maintain a healthy weight.
Obesity or overweight can increase the pressure on the joints; on the other hand, excess fat can cause inflammation, which can aggravate the symptoms
.
Evidence shows that weight loss can reduce pain and improve physical function and mobility
.
For people who are overweight or obese, a 10% weight loss will bring good benefits
.
Osteoarthritis is associated with type 2 diabetes and cardiovascular disease; therefore weight loss can also help prevent or manage these diseases
.
It is recommended to control the BMI between 18.
5~24 kg/m²; the waist circumference of men should be controlled within 90cm, and the waist circumference of women should be controlled within 85cm
.
You can combine diet with exercise, because physical activity can help inhibit neurodegeneration and protect neurons
.
Image source: 123RF 2: Eat anti-inflammatory fats The long-chain omega-3 polyunsaturated fatty acids found in oily fish have anti-inflammatory properties and are likely to be beneficial to osteoarthritis
.
It is recommended to eat at least two servings of oily fish a week, such as sardines, mackerel, and salmon
.
If you cannot consume deep-sea fish, the British Dietitians Association recommends that you consider taking fish oil capsules every day to provide 450mg of EPA+DHA
.
Although strictly speaking this is not enough to fight inflammation, studies have shown that it can improve the pain of patients with knee arthritis
.
Omega-6 polyunsaturated fatty acids and saturated fatty acids have certain pro-inflammatory properties and may worsen symptoms.
Therefore, it is recommended to eat less sunflower oil, corn oil, lard and other animal fats
.
Eat fats rich in monounsaturated fatty acids, such as rapeseed oil, olive oil, and camellia oil
.
Three: Vitamin D supplementation.
Vitamin D is essential for bone and cartilage health
.
Although we can get some vitamin D from our diet, sunlight is the main source of it (subcutaneous 7-dehydrocholesterol is the provitamin D3, which can produce vitamin D3 when exposed to ultraviolet light)
.
Studies have shown that vitamin D may have a positive effect on muscle strength, balance and weight management
.
The vitamin D we get daily is far from enough, so the British Dietitian Association recommends taking vitamin D supplements (10-25 micrograms) daily, especially in winter
.
Source: 123RF four: eat antioxidant vitamins antioxidant vitamins may reduce the occurrence of osteoarthritis oxidative stress, such as vitamin A, C and E
.
Although the evidence for the role of these vitamins in osteoarthritis is weak, they can be used as part of a healthy and balanced diet
.
The rich sources of vitamin A are: carrots, sweet potatoes, liver, etc.
The recommended intake (RNI) is 600-700 micrograms of retinol equivalent/day
.
Foods with rich sources of vitamin C include: citrus fruits, green peppers and red peppers, etc.
RNI: 40 mg/day
.
Foods with rich sources of vitamin E include: whole-wheat grains, nuts and seeds, with a safe intake of 3 to 4 mg/day
.
Foods with rich sources of vitamin D include: oily fish, egg yolks and certain nutrient-fortified foods, RNI: 10 micrograms/day
.
Foods with rich sources of vitamin K include spinach, lettuce, broccoli and Brussels sprouts.
The safe intake is 1 microgram per kilogram of body weight per day
.
In addition, it is recommended to eat 30g of nuts a day, 25g of soy protein, such as tofu, soy milk, soybeans / soybean and so on
.
Recommended reading Is Joint Pain Is Gout? These types of arthritis may also cause more than 3 million Parkinson's disease patients in China: not just "shaking hands".
What is a tumor? What is cancer? What's the difference? This article will take you to understand that the intestines are healthy without constipation? Make the "second brain" healthier and don't ignore it! The American Heart Association publishes that 80% of re-strokes can be prevented, the key is to do these reference materials [1] Shih-Hao Feng, Hung-Jui Chuang, Kuo-Cheng Yeh, Shin-Liang Pan (2021).
Osteoarthritis is associated with an increased risk of Parkinson's disease: A population-based, longitudinal follow-up study.
Arthritis Care & Research.
[2] Osteoarthritis: A Link With Parkinson's?.
Retrieved June 9, 2021, from https:// com/rheumatology/arthritis/92998[3] Osteoarthritis and diet: Food Fact Sheet.
Retrieved June 10, 2021, from https:// Healthy Eating for Knee Osteoarthritis.
Retrieved December 04, 2020, from https:// Note: This article aims to introduce the progress of medical and health research, not a treatment plan recommendation
.
If you need guidance on the treatment plan, please go to a regular hospital for treatment
.
