Panax notoginseng has strong pharmacological action and great potential for price rise

Sanqi has the effect of removing blood stasis, hemostasis, detumescence and pain Indications: hemoptysis, hematemesis, hematemesis, hematochezia, metrorrhagia, traumatic bleeding, chest and abdomen stabbing pain, tumescence and pain "Compendium of Materia Medica" cloud: "37 hemostasis, blood, pain." "Jade pull medicine solution" cloud: "sanqiheying hemostasis, Tongmai blood stasis, blood stasis and collect new blood (1) Sanqi has the name of "hemostasis drug" It is more suitable to disperse blood stasis and stop bleeding without retaining blood stasis Panax notoginseng has a strong hemostatic effect It has obvious hemostatic effect on different animals, different ways of administration and different preparations (2) the antithrombotic Panax notoginseng has the effect of promoting blood circulation and removing blood stasis, and can resist platelet aggregation and antithrombotic formation The active ingredient is Notoginsenoside, mainly ginsenoside Rg1 The content of plasma fibrinogen in patients with hyperviscosity or (and) hyperlipidemia can be significantly reduced by using San Qi powder Panax notoginseng can inhibit the conversion from fibrinogen to fibrin induced by thrombin, activate urokinase and promote the dissolution of fibrin The above results show that the antithrombotic action of Panax notoginseng includes anti platelet aggregation, antithrombin and fibrinolysis (3) promote the blood production of Panax notoginseng, which has been proved to have the effect of nourishing blood by modern research After 60Co - γ - ray irradiation, PNS was injected intraperitoneally for 6 days, which had a significant effect on the proliferation of pluripotent hematopoietic stem cells In the spleen nodule, granulocytes and erythrocytes had active mitosis, and the weight of spleen increased It can also promote the recovery of mice leucopenia and PNS induced by cyclophosphamide In rats with acute hemorrhagic anemia, Sanqi injection can significantly promote the recovery of red blood cells, reticulocytes and hemoglobin (4) effect on cardiovascular system Sanqi can disperse blood stasis, reduce swelling and pain, PNS and other active ingredients have extensive pharmacological activities on cardiovascular system Effects on the heart: PNS was injected into anesthetized cats or vena cava to significantly reduce the left ventricular internal pressure (LVP), the maximum rate of left ventricular internal pressure rise (DP / dtmax), the time to peak (t-dp / dtmax) was significantly prolonged, the heart rate was slowed down, the total peripheral vascular resistance and blood pressure were significantly decreased, but the cardiac output (CO), heart index and heart beat index were not decreased or increased The above results show that PNs has the effects of reducing myocardial contractility, slowing heart rate, expanding external blood vessels and reducing peripheral resistance Removal of Rg1 and RB1 from PNS and intravenous injection of the rest (Rx) rats had similar effects on hemodynamics PNS can antagonize the increase of contractile force and contractile frequency caused by CaC12, shorten the plateau period of action potential, indicating that PNs has the effect of calcium channel block The total flavonoids of Panax notoginseng, Panax notoginseng and the extract of Panax notoginseng root can resist the increase of T wave caused by acute myocardial ischemia in rabbits induced by pituitrin In dogs with experimental acute myocardial infarction, Sanqi injection can significantly reduce ST segment shift and pathological Q wave In the experiment of acute myocardial ischemia induced by ligation of coronary artery in rabbits, PNS was injected intravenously before ligation and 5 minutes after reperfusion, which could significantly improve the ECG of ischemia and reduce the area of myocardial infarction PNS can reduce the infarct area and inhibit the further increase of serum creatine phosphokinase (CPK) (5) anti inflammatory PNS has an obvious inhibitory effect on the increase of capillary permeability caused by histamine, acetic acid, xylene, 5-hydroxytryptamine and bradykinin The main effective component of anti-inflammatory is saponin, mainly panaxadiol saponin The anti-inflammatory effect is related to the pituitary adrenal system PNS can decrease the content of vitamin C in the adrenal gland of rats and increase the concentration of corticosteroids in the plasma of guinea pigs after intraperitoneal injection of PNS However, the anti-inflammatory effect of PNS on adrenalectomized rats is still obvious, which indicates that the anti-inflammatory effect of PNS is not entirely dependent on the pituitary adrenal system (6) Panax notoginseng has the effect of anti liver injury PNS can significantly reduce the serum ALT activity of CCl4 liver injured mice Methanol extract can significantly reduce AST and LDH activity in serum of CCl4 and D-galactosamine-induced liver injury rats, and reduce the degeneration and necrosis of hepatocytes Panax notoginseng also has the effect of anti liver fibrosis It can reduce the degeneration and necrosis of hepatocytes and the collagen fibers between hepatocytes in rats poisoned by dimethylnitrosamine after 4 weeks of treatment with Panax Notoginseng Powder Panax notoginseng can promote the synthesis of liver protein, increase the incorporation rate of 3H TDR into DNA of damaged liver, and increase the incorporation rate of 3H leucine into liver protein (7) the anti-tumor ginsenoside Rh1 has an inhibitory effect on hepatoma cells in vitro Ginsenoside RH can inhibit the growth of mouse melanoma (B16) in a concentration dependent manner PNS can enhance the killing ability of the activated immune cells, which may be the reason why PNS can enhance the antitumor activity of the activated immune cells (8) analgesic notoginseng is a commonly used medicine for the treatment of injuries caused by falls, which has a definite analgesic effect It has analgesic effect on many kinds of pain models, such as writhing method of mice, hot plate method and tail flick method of rats Panaxadiol saponin is the effective component of analgesia Since last year, especially since the spring of this year, the market of notoginseng, a precious Chinese herbal medicine, has risen rapidly, which has attracted the attention of many businesses At the end of the 1980s, the price of 37 once reached more than 300 yuan With the calming down of the rising price, the price of 37 fell rapidly and fell to more than 40 yuan at the end of 1989 At present, the market of March 7th is stable Since the new production, the listing volume is not large, and it is generally expected that this year's production will be further reduced As a result, people are optimistic about the aftermarket, and generally reluctant to sell, resulting in the price of March 7th higher Sanqi has high cost, high value and high popularity It still has the potential to rise for the future market of Sanqi.