【Pain topic】Ropivacaine is used for half the effective dose of pediatric ultrasound-guided median nerve block

Methods: Eligible children were American Society of Anesthesiologists (ASA) status I–II scheduled to have elective open surgery for trigger thumb repair.
Patients were stratified into two age groups: 1- to 3-yearolds and 3- to 6-year-olds.
The ED50 was determined by Dixon’s up-and-down method.
The first patient received an ultrasound-guided median nerve block by injection of 2 mL of 0.
2% ropivacaine.
Each subsequent patient’s dose was determined by the response of the previous patient, the doses being adjusted in intervals of 0.
2 mL.
In addition, the 95% effective dose (ED95) was obtained using a probit regression approach.
The patients’ general condition, postoperative pain scores, and adverse events were recorded.

Methods: Eligible children were American Society of Anesthesiologists (ASA) class I-II and were scheduled for selective open surgery for thumb trigger repair
.
Patients were divided into two age groups: 1-3 years and 3-6 years
.
ED50 is determined
by Dixon's up-and-down method.
The first patient received a median nerve block with ultrasound-guided injection of 2 ml of 0.
2% ropivacaine
.
The dose for each subsequent patient is determined by the response of the previous patient, and the dose is adjusted
at 0.
2 mL intervals.
In addition, 95% of the effective dose (ED95) was obtained
using probabilistic regression methods.
The patient's general condition, postoperative pain scores, and adverse events
were recorded.