Pain: stem cell therapy is the first success!

January 26, 2020 / Biovalley bio on / - recently, researchers at the University of Sydney have developed neurons that can relieve pain using human stem cells, providing lasting relief in mice through one treatment without side effects Next, the authors plan to conduct a wide range of safety tests on rodents and pigs, and then move to treatment in humans with chronic pain over the next five years If these tests are successful in humans, they could be a major breakthrough in pain management strategies for non addicts, the researchers said (image source: www Pixabay Com) Associate Professor Greg Neely, author of the article and director of pain research at the Charles Perkins center and the school of life and Environmental Sciences, said: "neurological damage can lead to devastating neuropathic pain, and for most patients, there is no effective treatment This breakthrough means that for some of these patients, we can find ways to relieve pain from our own cells " The results, published recently in the journal pain, showed that the team used human induced pluripotent stem cells (iPSCs) derived from bone marrow to prepare analgesic cells in the laboratory and then put them into the spinal cord of mice with severe neuropathic pain Dr Leslie Caron, CO senior author, said: "it is worth noting that stem cell neurons can promote long-lasting pain relief without side effects." "This means that transplant therapy may be an effective and lasting treatment for neuropathic pain It's very exciting " Dr John Manion, co-author of the paper, said: "because we can choose where to put the pain neurons, we can only target the body parts in the state of pain This means that our approach can reduce side effects " Source of information: first treatment for pain using human stem cells a success original source: John Manion et al Human induced pluripotent stem cell derived GABAergic interneuron transplants attached neuron pain, pain (2020) Doi: 10.1097/j.pain.0000000000000000001733