Onion extract can improve blood sugar and cholesterol

Recently, at the 97th meeting of the American Society of Endocrinology held in San Diego, researchers from Delta State University said that when combined with metformin, an antidiabetic drug, onion extract can significantly reduce the blood pressure and total cholesterol level of diabetic rats The researchers said the onion extract, which is easy to obtain and is often used as a nutritional supplement, showed potential uses in the treatment of diabetes The researchers divided the drug-induced diabetic rats into three groups, and gave metformin plus different doses of onion extract 200 mg / kg, 400 mg / kg and 600 mg / kg every day, respectively, to observe whether this combination would enhance the efficacy; at the same time, the researchers divided the normal blood glucose non diabetic rats into three groups, five rats in each group, fed two rats respectively Metformin and onion extract were used as control, and two control groups were set up, i.e a non diabetic group and a diabetic group The mice in these two groups did not receive metformin or onion extract The results showed that 400 mg / kg and 600 mg / kg onion extracts could significantly and rapidly reduce the blood glucose level of diabetic rats, with the proportion of 50% and 35%, respectively (compared with the reference level) It has been reported that onion can reduce the total cholesterol level of diabetic rats, and the study found that the above two doses have a very significant effect on cholesterol reduction; however, researchers found that onion extract can increase the average weight of non diabetic rats, but has no effect on diabetic rats According to the researchers, onion is not high in calories, but it may increase the metabolic rate of rats, thus increasing their appetite, thus leading to an increase in rat feeding; histological examination of pancreas removed from each diabetic rat showed that neither metformin nor onion extract could cure the drug-induced damage of rats "We need more in-depth research to explain the molecular mechanism of onion extract to reduce blood sugar The onion extract used as the experiment is a crude extract from onion stem If it can be applied to human mechanism, then we will purify it to obtain effective ingredients that can be more effective and sufficient for clinical trials of human body," the researchers said.