Oncoimmunol: Immunotherapy can be used to treat malignant skin cancer.

9, 2020 /--- According to a recent study published in the journal OncoImmunology, researchers at the Karolinska Institute and the hospital have shown that new immunotherapy has significant effects on the treatment of malignant melanoma.
James Allison and Tasuko Honjo were awarded the Nobel Prize in Medicine for developing immunotherapy for oncology.
, however, most patients with advanced malignant melanoma do not respond well to immunotherapy.
(photo source: www.pixabay.com) In a recent study, researchers extracted "tumor-soaked lymphocytes", or TIL cells, from the patient's own tumor.
TIL volume increased to 50 billion through in-body amplification, it was mixed with growth factor Interleukin-2 and then returned to the patient.
", compared to other TIL-related clinical trials, is unique in that patients are also treated with multiple doses of tumor vaccine made up of destill cell DC, which is designed to activate the immune system and get injections of TIL cells to Karolinska Institute of Oncology Pathology researcher Stina Wickstr?m.
three of the four patients treated with severe severe malignant melanoma who were treated in a joint treatment with the TIL cell and DC tumor vaccine received complete or almost complete remission.
patients treated with TIL cells alone were less satisfied with the treatment than those treated in cooperation with the tumor vaccine.
The method is part of the enhanced cell therapy at Karolinska University Hospital, and the head of research, Rolf Kiessling, has applied to the Swedish Medical Products Agency for approval and can also test the method on other types of metastatic cancer.
(bioon.com) Source: New type of of the therapy show for advanced skin cancer Source: L?vgren, T., et al. (2020) Complete and long-lasting clinical responses in immune checkpointor-resistant, metastasized melanoma treated with the use of Tive cell transfer combined with DC. OncoImmunology. doi.org/10.1080/2162402X.2020.1792058.