On May 26th, something big happened in China's lactic acid bacteria industry...

.

2016, the global output value will reach
42
billion U.S. dollars. . . probiotic industry as a pioneer in the health transformation of the food industry. . . the 11th International Symposium on Lactobacillus and Health held in Shijiazhuang In the past ten years, the structure, function and characteristics of intestinal microorganisms have received unprecedented attention, people have begun to realize the important position of probiotics in micro-ecological theory, and the complex interaction between
-
intestinal bacteria
-
-host health" has been studied by more and more scholars at home and abroad. Academic blooms have kept the industry growing at an average annual rate of
15-20%
in China, consistently higher than the growth rate of China's food industry. Probiotic-related products are also one of the fastest growing categories in the global functional food market, with data showing that
the probiotics industry generated $
28
.8 billion in global production in
and is expected to grow to
$
42 billion in 2016In order to further understand the latest research results in the field of probiotics, the development trend of the pulse industry, sponsored by the China Food Science and Technology Association, China Food Science and Technology Association Lactobacillus Branch, Hebei University of Science and Technology, Hebei Food Society hosted the "11th International Symposium on Lactobacillus and Health" at
2
may



26-27
, 2016 in Shijiazhuang, attended by more than
,300,
people from industry authorities, academic representatives and the business and media sectors. Inspector Wang Wei of the Rural Science and Technology Department of the Ministry of Science and Technology, Deputy Director of the Hebei Provincial Science and Technology Department Li Zhimin and Vice President Jia Yingmin of Hebei University of Science and Technology attended the opening ceremony and delivered speeches, with experts from Canada, Ireland, the Netherlands, Japan and Taiwan sharing the latest research results in the fields of probiotics and intestinal micro-ecology, probiotics and disease prevention, and functional research of probiotics.China Food Science and Technology Association Meng Suho Chairman said at the meeting, with the "nutrition and health" dual gene probiotic industry in China in just over a decade of growth, has now developed into a driving force to drive China's food industry to cope with the downshoot of the economy, which also shows that China's food industry needs to accelerate the transition to nutrition and health.probiotic industry - a useful reference on the road of supply-side reform a major feature of China's probiotic industry development is that from the beginning of development there are a large number of outstanding scientists for its solid scientific research foundation.
In
, 2005, the Lactobacillus Branch of the China Food Science and Technology Society was established, which assembled China's best industry scientists, starting with studying foreign cutting-edge basic research, and gradually groping out a "successful way" for scientific research in the field of probiotics in China. Eleven years have passed, China's lactic acid bacteria in the field of scientists through their own efforts, with a high impact factor paper and a research results of great value, gradually in line with international standards, some of the research results in the food industry successfully transformed, promoting the rapid growth of the entire industry.At the meeting, Inspector Wang Wei of the Rural Science and Technology Department of the Ministry of Science and Technology said that the Ministry of Science and Technology has always attached great importance to the development of science and technology and support capacity-building of my probiotic industry, and deployed a number of major and key projects during the "11th Five-Year Plan" and "12th Five-Year Plan" period, promoting basic research and industrialization of the industry, and shortening the gap between China's probiotic products processing technology and the international advanced level. During the "13th Five-Year Plan" period, we will further promote the transfer and transformation of scientific and technological achievements by stimulating the main body of innovation, perfecting the service system for the transfer and transformation of scientific and technological achievements, carrying out the information exchange and release of scientific and technological achievements, exerting the important role of the local government in promoting the transfer and transformation of scientific and technological achievements, and strengthening the deep integration and optimal allocation of innovative resources.Thus, the scientific and technological investment in the field of probiotics will continue to expand in the future, especially in the transfer and transformation of scientific and technological achievements will be further intensified, probiotics industry as a perfect embodiment of science and technology in the food industry" "model", will continue to optimize the existing scientific and technological achievements transfer and transformation system, for the food industry to provide useful reference for the road of supply-side reform.Basic Research - In-depth Focus on Probiotics and Intestinal Microeconscilation 1
, Intestinal Microbiology and Host Health Research EscalatingDuring the meeting,
Catherine Stanton
, Chief Research Officer of the Irish Department of Agriculture and Food Development, shared her findings in recent years on the effects on metabolites and host health produced by gut microorganisms. According to him, gut microorganisms themselves can produce nutrients including
VB
,
VK
and a large number of healthy metabolites, in addition, evidence that microorganisms can produce neuroactive functional molecules has been gradually discovered, these active molecules play a role in regulating the transmission of signals in the intestinal nervous system, further affecting brain function and behavior.colorectal cancer is one of the most common high-fatal cancers, and studies in recent years have found that multiple intestinal bacteria and inflammatory bacteria disorders can exacerbate the development of colon cancer. Professor Zhang Peace, Director of the Key Laboratory of the Ministry of Education of "Dairy Biotechnology and Engineering" of Inner Mongolia Agricultural University, opened up new ideas for the prevention and treatment of colon cancer, based on many years of animal test data, explored practical ways to use probiotics to reduce colon cancer, and explored the mechanism by which probiotics prevent colon cancer, providing scientific and technological support for probiotics to prevent colon cancer.
Anna Lyra
, Senior Scientist, Global Health and Nutrition Research Team, DuPont Nutrition and Health, presented recent research on the clinical efficacy of probiotics in humans, including: Lactobacillus acidophilus
NCFM
to relieve visceral pain and support
intestinal health
; Lactobacillus
HN001




is implanted in the vagina to support women's health; In addition, beneficial changes in the gut microbiota of colon cancer patients who ate Lactobacillus acidophilus
NCFM
and C.D.
Bl-05
were also found.the latest test results on
LcS
probiotic strains withHao and the lead researcher from the Central Research Institute of The Company. He said that
LcS
probiotics have significant improvement effects on many health characteristics such as preventing cancer in patients with colorectal pliers, inhibiting the occurrence of mutated tumors in patients with colorectal cancer removal, anti-inflammatory effects on chronic enteritis symptoms, improving detox and abdominal symptoms in hard bowel populations, and enhancing the activity of natural killer cells in smokers.2
Genomics provides a powerful technical tool for probiotics and intestinal micro-ecological researchmacrogenomics provides a thorough understanding of the entire gut microbiome. There are many relevant research programs at home and abroad, such as the
MetaHIT
in the European Union, which aims to establish a relationship between gut microbiome genes and human health diseases. The United
States launched a similar human microbiome
HMP
in
2008 with a total budget of $
115
billion over a five-year period. The ultimate goal of this project is to test changes in the human bacteria and their association with human health or disease. In China, the state has approved a research program on intestinal microorganisms associated with infectious diseases, which aims to study changes in gut microorganisms in infectious diseases using methods of systems biology, including macrogenomics and metabolomics. Qin Nan, from Zhejiang University's Center for Collaborative Innovation in Infectious Diseases, studied the gut bacteriosty of
98,
patients with cirrhosis and
83,
healthy people using quantitative macrogenomic technology. The first reference gene set for cirrhosis was established, including
2.69
million genes, of which
36.1%
was a new gene; Biomarkers consisting of
15,
genes establish a new standard for the diagnosis of liver cirrhosis bacteriosobacteria imbalance (
PDI
index) and have been validated in an independent group as a powerful tool for diagnosis of cirrhosis. Professor
Michael G. Gänzle
, Dean of the Department of Food Science and Biological Resources, University of Alberta, Canada, conducted a detailed study of the different classifications of lactic acid bacteria in grain fermentation using genomics-related analytical techniques, with special functional lactic acid strains and their different effects on product quality, flavor, and nutritional function. The Zhong Qi team of the Institute of Microbiology of the Chinese Academy of Sciences carried out a genetic engineering transformation of the lactic acid bacteria
NICE
expression system, and simultaneously constructed the components and target proteins required for the
NICE
system into a single vector, transforming lactic acid lactobacillus lactobacillus and establishing a new and more simple and stable
NICE
protein expression system. The optimized
NICE
system has great application potential for improving protein expression and reducing production costs, and the ease of operation of individual protons makes it possible to apply in other hosts that are relatively sensitive to
nisin
, expanding the range of applications of
NICE
systems. 3
, infant gastrointestinal health and growth and development caused by hot discussion meeting, with the support of Yili Group, the Chinese Food Science and Technology Society again organized probiotics and infant gastrointestinal health topics, invited from Hebei Medical University, Beijing Children's Hospital and related experts from Denmark, the United States from their respective research areas, to explore probiotics and infant gastrointestinal health, Chinese infant gastrointestinal health and other content. present, China's newborn birth rate is the highest in the world, the birth population will grow rapidly after the liberalization of the second-born policy, infant formula dairy market has great potential, but consumer recognition of foreign products is still higher than domestic products. Through basic research to promote the development of infant formula milk powder market is an inevitable way to develop, experts pointed out that through a large number of basic research, design and optimization of formula, to produce more suitable for the Chinese baby body of infant formula milk powder, is one of the important tasks of the current industry. application and industrialization - to promote the development of scientific research achievements in the field of probiotics to take root Probiotics as a diversified sunrise industry, has covered food, medical, aquaculture, environmental protection and other fields. The establishment of its resource bank, the development of excellent probiotics with independent intellectual property rights, high-density culture technology, ultra-concentrated preparation technology, freeze-drying protection technology, direct-investment fermentation preparation technology and other key technologies research and application, to promote the industry in new technologies, new equipment, new products research and industrialization. Probiotic industry is gradually breaking through the yogurt and lactic acid beverage as the main carrier of the product pattern, and gradually to health food, infant milk powder, kimchi, candy, cheese, probiotic preparations and other diversified products to open up new market space. During the meeting, with the support of Junlebao Dairy Co., Ltd., the China Food Science and Technology Association launched the "Probiotics
plus
" strategy launch ceremony, which aims to promote the application and industrialization of probiotics in various fields, so that the health benefits of probiotics benefit the entire food industry. As Professor Chen Wei, chairman of the Lactobacillus Branch of the China Food Science and Technology Society and dean of Jiangnan University's School of Food, said: "Build a high-end platform for the integration of production, research and development around the strategy of
probiotics" and "
" to realize talent innovation, product innovation and industrial model innovation." This requires the government, enterprises, academic circles and all sectors of society, starting from all aspects of the industry upstream and downstream, around nutrition and health to work together, out of a Chinese market characteristics, the needs of Chinese consumers innovative development path. At the , in order to meet the development needs of the probiotic industry, strengthening close collaboration between enterprises and scientific research institutions is a top priority. Professor Zhang Lanwei of Harbin University of Technology has a very "grounded gas" view on the industrialization of lactic acid bacteria. He said that the core of fermentation agent is lactic acid bacteria, with the help of current biotechnology means, to build lactic acid bacteria fermentation agent strain resource bank, explore or develop on the basis of existing lactic acid bacteria, with functional, new high-efficiency lactic acid bacteria fermentation agent, or the use of lactic acid bacteria relationship, research and development of fermentation agents containing more bacteria, is conducive to improving the fermentation process, improve product quality, achieve product diversification. addition, probiotic-related products have been extended to the field of health food.


26 2016

and will be released
July
2016