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International war "epidemic" operation
A few days ago, a number of Israeli media reported that at least 20 cases of infection with the BA.
2 variant of the new coronavirus Omicron strain were found in the country.
concerns of some experts
.
Coincidentally, recently, a number of researchers tracking the evolution of the new coronavirus warned on social media that the BA.
2 variant of the Omicron strain is making waves in many countries, and even began to gradually replace the earlier BA.
1 variant
.
This "involution" suggests that the BA.
2 variant may be more infectious
According to the new coronavirus genome data uploaded to the GISAID platform by various countries, the BA.
2 variant was very rare until mid-December 2021, but the number has risen rapidly since then
.
In Denmark, from December 30 last year to January 2 this year, the BA.
2 variant increased from 14.
According to a related article published in China CDC Weekly on January 3 by researchers from the Guangdong Provincial Center for Disease Control and Prevention, the world's earliest BA.
2 variant sample was found in South Africa on November 27, 2021, and on December 28 On January 1, the Guangdong Provincial Center for Disease Control and Prevention found that an imported case from abroad was infected with the BA.
2 variant.
Gene sequencing analysis showed that the variant had 67 nucleotide mutation sites and 49 amino acid mutation sites at the protein level.
and 9 amino acid deletions
.
The BA.
1 variant has about 50 variants at the protein level, which is slightly less than that of the BA.
It is worth noting that the BA.
1 variant will appear off-target of the spike protein gene in PCR detection, which is an important feature that distinguishes it from strains such as "Delta", so it is easier to find
.
However, the BA.
2 variant genome does not have the characteristic deletion that leads to the off-target of the spike protein gene.
In fact, the Omicron strain also has a BA.
3 variant, but the number is small, with only 33 samples found worldwide
.
At present, researchers in Israel and other countries are closely tracking the spread of the BA.
2 variant of the Omicron strain, and its infectious and pathogenic characteristics are still under study