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Olapari reduces risk of death by 32% in selected early-stage breast cancer patients

 Last Update: 2022-04-28
 Source: Internet
 Author: User

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A few days ago, AstraZeneca and Merck announced more positive results from the Phase 3 clinical trial OlympiA of the PARP inhibitor olaparib (Lynparza) jointly developed by the two parties

Breast cancer is one of the most common cancers worldwide, with more than 2.

BRCA is an important protein for repairing cellular DNA damage, and PARP also plays an important role in repairing DNA damage

On the key OS endpoint, olaparib reduced the risk of death by 32% compared with placebo (HR=0.

The primary endpoint results of the Phase 3 clinical trial of OlympiA have been published in the New England Journal of Medicine

References:

[1] LYNPARZA® (olaparib) Reduced Risk of Death by 32% in Patients With Germline BRCA-Mutated, HER2-Negative High-Risk Early Breast Cancer in Phase 3 OlympiA Trial.

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