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    Home > Active Ingredient News > Immunology News > Often mouth ulcers, with these symptoms? Beware of white-stuffed disease!

    Often mouth ulcers, with these symptoms? Beware of white-stuffed disease!

    • Last Update: 2020-07-23
    • Source: Internet
    • Author: User
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    Don't want to miss Jiemei's push? It is a typical symptom of Behcet's disease to poke the "rheumatism and nephropathy channel of medical circles" on the top of the blue character to pay attention to us and click the "··" menu in the upper right corner and select "set as star" to repeat oral ulcer.speaking of Behcet's disease, many people may not be familiar with it. Behcet's disease is a kind of vasculitis. Most patients only invade the small blood vessels under the mucosa and cause mucosal ulcer. However, a few patients with Behcet's disease will involve large and small blood vessels of the whole body, causing damage to large blood vessels or internal organs, which will be life-threatening.generally speaking, most of the female patients were mild, mainly mucosal ulcer, while the male patients were more serious, often involving visceral vessels.although Behcet's disease is still an incurable disease at present, standardized anti-inflammatory and immunotherapy can often achieve the effect of relieving the disease.today, Professor Yang Xiuyan, Department of Rheumatology and immunology, the First Affiliated Hospital of Sun Yat sen University, will introduce in detail to you that when we have any symptoms, we should be careful of Behcet's disease.oral ulcer is a typical symptom of Behcet's disease.almost everyone has developed oral ulcer, but most people's oral ulcer is transient and accidental, or it is caused by accidentally biting oral mucosa. This kind of oral ulcer only needs to pay attention to rest and eat more fruits and vegetables, which can self heal.but if it is a long-term recurrent oral ulcer, or even one after another, it is necessary to check whether there are autoimmune diseases, especially Behcet's disease.if there are more than three times of oral ulcer every year, accompanied by the following conditions, Behcet's disease needs to be vigilant, and it is recommended to go to the Department of Rheumatology and immunology. According to Professor Yang Xiuyan, the most common symptoms of Behcet's disease are oral ulcer and vulvar ulcer.vulvar ulcer includes genital ulcer and perianal ulcer.If genital ulcer occurs in glans and penises in men, the symptoms will be more obvious, but the symptoms of scrotal ulcer will be mild.female genital ulcer can occur in labia, labia and vaginal wall. The symptoms vary in severity, and some even have no symptoms, which can only be found by gynecological examination.clinically, many genital ulcers of Behcet's disease are often misdiagnosed as venereal diseases, which can not be cured for a long time.if these patients are accompanied by frequent oral ulcers, they may not be venereal diseases, but Behcet's disease. Behcet's disease often invades the eyes. In the early years, Behcet's disease was called "eye, mouth and genitalia syndrome".according to Professor Yang Xiuyan, the symptoms of the eye are various. Uveitis is often involved in the early stage, especially iridocyclitis. The patients with uveal involvement often have poor vision without other eye symptoms, which can only be judged by ophthalmic examination. Behcet's disease can also be conjunctivitis, scleritis, keratitis, etc., and serious cases can be secondary to glaucoma and vitreous Opacity, fundus retinitis, optic neuritis, etc.the main clinical symptoms are red eye pain, vision loss, photophobia and tears, foreign body sensation, flying mosquito disease and headache, etc., which are usually chronic, recurrent and progressive, and the blindness rate can reach 25%.if there are ophthalmic diseases, which have not been cured or recurred for a long time, accompanied by frequent oral ulcers (more than 3 times a year), Behcet's disease should be alerted, and it is recommended to consult the Department of rheumatology and immunology. According to Professor Yang Xiuyan, Behcet's disease may also be manifested on the skin, such as severe acne, nodular erythema, difficult wound healing and acupuncture reaction. if there are a lot of acne, and most of them have redness and pustules, which last for a long time and are accompanied by frequent oral ulcers, we should be highly vigilant against Behcet's disease. erythema nodosum mainly occurs in the lower limbs, but also in other parts of the body. If erythema nodosum is accompanied by frequent oral ulcer, Behcet's disease should be noted. even without oral ulcer, we should pay attention to other rheumatic diseases. Behcet's disease is characterized by difficulty in healing the wound. this kind of patients is common in clinic. The wound is suppurative and difficult to heal. According to the conventional thinking, the doctor thought it was infection, and the use of a large number of antibiotics was ineffective. After asking the patient's medical history, he found that the patient had a history of frequent oral ulcer and was diagnosed as Behcet's disease. Only by readjusting the treatment direction can the wound heal. similarly, patients with Behcet's disease may have small swelling or small pus spots lasting more than two days during injection or blood drawing. This phenomenon is called "acupuncture reaction" and is an important feature of Behcet's disease. Oral ulcer + joint pain some Behcet's disease patients have mild oral ulcer, which only occurs 3-5 times a year, which will not be a reason for seeking medical treatment, while joint pain is more perplexing to patients' life. if joint pain and recurrent oral ulcer occur, Behcet's disease should be noted. 5. Oral ulcer + vascular problems Behcet's disease itself is a kind of vasculitis, and its oral ulcer is caused by the inflammation of small vessels under the oral mucosa. although most patients only damage the mucosa, some patients may develop vasculitis in other parts of the body. the main vascular diseases of Behcet's disease are arteritis and phlebitis, which can lead to arterial stenosis and infarction, aneurysm, venous thrombosis, etc. therefore, unfortunately, patients with vasculitis need to recall whether they have recurrent oral ulcers, and if so, inform your doctor in time, so as to avoid detours in the process of diagnosis and treatment. Oral ulcer + valvular heart disease most heart valve diseases are caused by rheumatic fever caused by Streptococcus infection in the throat of children and adolescents, which is called "rheumatic heart disease". Professor Yang Xiuyan introduced that Behcet's disease can also cause serious heart valve disease, most of which start after young adults, and the disease develops rapidly. Intractable heart failure occurs within a few months. Cardiac surgeons have to operate on patients to replace artificial heart valves. but because Behcet's disease itself is prone to aseptic abscess and the wound is not easy to heal, it often appears that "the operation is very successful", but after the operation, the artificial valve is unstable or falls off within a few months, resulting in the patient's death. if we can correctly diagnose "heart valve disease caused by Behcet's disease" before operation, invite rheumatology and Immunology Department for consultation, carry out anti-inflammatory and immunotherapy, and control disease activities, the success rate of treatment will be greatly improved. 7. Oral ulcer + chronic pulmonary embolism Behcet's disease is also characterized by easy thrombosis. Thrombus in venous system and thrombus in right heart fall off, which can lead to pulmonary embolism. chronic pulmonary embolism caused by Behcet's disease, if anticoagulant and thrombolytic therapy are used in the conventional treatment of chronic pulmonary embolism, it is often difficult to work, and anti-inflammatory and immunotherapy must be carried out simultaneously. Professor Yang Xiuyan introduced that he often saw some patients with abdominal pain, diarrhea or intestinal bleeding, who were diagnosed as ulcerative colitis or Crohn's disease in the digestive departments of many hospitals, but the treatment effect according to colitis or Crohn's disease was not good. after consultation with rheumatic immunology doctors, the diagnosis of Behcet's disease was corrected.
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