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According to a recent study published in the leading academic journal Cell, some digestive tract diseases, characterized by intestinal inflammation, are closely related to oral health! Researchers from the University of Michigan School of Medicine and the School of Oral Medicine in the United States found that the bacteria in the mouth that cause periodontitis are likely to be a key factor in exacerbating inflammatory bowel diseaseinflammatory bowel disease, including ulcerative colitis and Crohn's disease, the symptoms are frequent abdominal pain, severe diarrhea, blood stool, etcThis is a common chronic disease whose cause is not clearWorldwide, there are more than 12 million people with inflammatory bowel disease, and the incidence of such diseases has increased significantly in China for more than a decadeis often thought to be associated with inflammatory bowel disease and loss of balance in the intestinal floraProfessor Nobuhiko Kamada, lead author of the study, has studied gut flora for years, but he notes a previously unknown link: in the intestines of patients with inflammatory bowel disease, overgrown foreign bacteria appear to be associated with bacteria commonly found in the mouth"I decided to go to the stomatology school and ask if oral problems can affect the severity of intestinal disease." Professor Kamada saidresults led scientists to find that oral bacteria not only interfere with the intestines, but also exacerbate inflammation in the intestines in two waysa way to come directly from bacteria associated with periodontitisPeriodontitis, also known as gum disease, is characterized by bleeding gums and abscesses, loose teeth, and is a common chronic inflammation that affects nearly 11% of the world's populationPeriodontitis causes a large increase in the number of bacteria causing inflammation by outputting the balance of normal and healthy oral floraThese disease-causing bacteria are swallowed into the intestines with saliva, however, that alone is not enough to trigger inflammation of the intestines"Normal intestinal flora can resist the implantation of foreign bacteria, " explains Professor Kamada" The researchers looked at changes in the intestinal flora of mice with colitis and saw that oral pathogenic bacteria could make intestinal inflammation worseWhen mice suffered from both periodontitis and intestinal inflammation, the weight loss was significantly reduced, and symptoms such as fecal abnormalities also occurred more, periodontitis activates T-cells in the mouth of the immune system And these oral T-cells enter the intestines, also causing increased inflammation normal intestinal flora is balanced by inflammatory T cells and regulatory T cells However, most inflammatory T cells produced by inflammation of the mouth are transferred to the intestines, where they eventually trigger an immune response in the intestines, worsening the disease recent studies have shown that oral health can reflect a person's overall health, from heart disease to diabetes, many systemic diseases are associated with poor oral health Professor William Giannobile, an oral medicine expert and co-author of the study, said: "This finding makes it all the more important for us to stress to patients the importance of oral hygiene and that promoting oral health is an important part of good health "
inflammatory bowel disease is one of the high risk factors for colorectal cancer, and controlling inflammation of the intestine also means reducing the risk of bowel cancer To avoid "sickness from mouth to mouth," the new findings remind us to keep teeth and gums clean, such as brushing at least twice a day, and keeping teeth clean Even if you don't have gum disease, you should have regular oral exams and stop running away from the dentist!