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Ocular terminates cooperation with Regeneron to develop aflibercept sustained-release formulations

 Last Update: 2021-09-05
 Source: Internet
 Author: User

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Compiler: Fan Dongdong

A few days ago, Ocular Therapeutix and Regeneron announced the termination of their cooperation and the suspension of the development of aflibercept sustained-release preparations for the treatment of wet age-related macular degeneration (AMD) and other serious retinal diseases.
The decision to terminate will take effect on August 5, 2021.

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Ocular is a biopharmaceutical company specializing in the formulation, development and commercialization of innovative treatments for ocular diseases and disorders.
In 2016, the company and Regeneron launched an ocular treatment cooperation
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According to the cooperation agreement, Regeneron will use Ocular's hydrogel technology to develop and commercialize aflibercept and other targeted VEGF drug sustained-release formulations for ophthalmic indications

Antony Mattessich, President and CEO of Ocular Therapeutix said, “Although I regret the end of the cooperation, Ocular is very grateful for the opportunity to cooperate with Regeneron to develop aflibercept
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This cooperation may bring valuable strategic driving force for Ocular's future product lines.

As a VEGF inhibitor, aflibercept can block the growth of new blood vessels by blocking VEGF-A and placental growth factor (PLGF), two growth factors involved in angiogenesis, and reduce the ability of fluid to pass through blood vessels (vascular permeability).

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It is worth noting that aflibercept injection formulation is about to face the challenge of patent expiration in 2025
.

Currently, the main competitor of the drug in the market is Novartis Beovu (brolucizumab)

Reference source: Ocular Therapeutix™ Announces Termination of the Collaboration with Regeneron to Develop a Sustained-Release Formulation of Aflibercept for the Treatment of Wet AMD and other Serious Retinal Diseases

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