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November-December Nature magazine had to look at the heavyweight highlights study

 Last Update: 2021-01-03
 Source: Internet
 Author: User

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FAT1 is one of the most common mutation-driven genes in many cancers in humans.
the loss of function of the gene has shown that FAT1 has anti-cancer effects and can prevent the production of cancer.
, despite the high frequency of FAT1 mutations, little is known about its role in cancer.
In a new study, researchers led by Professor Cedric Blanpain, director of the Stem Cell and Cancer Laboratory at the Free University of Brussels in Belgium, have confirmed for the first time that the absence of FAT1 promotes EMT, immersion characteristics and metastasis in skin squamous cell carcinoma (the second most common cancer in humans), lung cancer (the deadliest cancer) and head and neck tumors.
the findings were published in the journal Nature.
: For the first time, doi:10.1038/s41586-020-3034-x organs (organoids) are laboratory-cultured stem cells derived from similar organ tissues, often referred to as micro organs.
they can simulate the structure and function of human organs, they are thought to be constructed

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