Novel coronavirus infection, inventory of 6 antiviral drugs!

01

Applicable population

It is an adult patient
with mild and moderate incidence within 5 days of onset with factors at risk for progression to severe disease.

Usage and dosage

Nematevir 300 mg is taken simultaneously with ritonavir 100 mg once every 12 hours for 5 days
.

Notes

Do not combine with drugs such as pethidine and ranozine that are highly dependent on CYP3A for clearance and whose elevated plasma concentrations can cause serious and/or life-threatening adverse reactions
.
It should only be used
during pregnancy if the potential benefit to the mother outweighs the potential risk to the fetus.
Not recommended for use
during lactation.
Patients with moderate renal impairment should take nimatevir by half, and patients with severe liver and kidney function impairment should not use it
.

02

Applicable population

It is used to treat adult patients
with medium-sized new coronavirus infection.

Usage and dosage

Swallow the whole tablet on an empty stomach, 5mg each time, once a day, the course of treatment is not more than 14 days
.

Notes

Pay attention to interactions with other drugs, adverse reactions and other problems
.
It is not recommended to use during pregnancy and lactation, and patients with moderate to severe liver and kidney function impairment should be used
with caution.

03

Applicable population

It is an adult patient
with mild and moderate incidence within 5 days of onset with factors at risk for progression to severe disease.

Usage and dosage

800 mg orally every 12 hours for 5 days
.

Notes

Not recommended during
pregnancy and lactation.

04

Applicable population

Combined for the treatment of mild, medium-sized adults and adolescents (12 to 17 years, weighing ≥ 40 kg) with risk factors for severe disease
.

Usage and dosage

The dose of the two drugs is 1000 mg
, respectively.
Before administration, the two drugs were diluted with 100ml of normal saline, administered by intravenous sequential infusion, intravenous drip at a rate of no more than 4ml/min, and a 100ml normal saline flush tube was used between them
.

Notes

The patient is clinically monitored during the infusion and observed for at least 1 hour after the completion of the infusion
.

05

Applicable population

Can be used early in the course of disease in patients with risk factors for severe disease, high viral load, and rapid disease
progression.

Usage and dosage

The dose used is light 100mg/kg, medium 200mg/kg, heavy 400mg/kg, intravenous infusion, according to the improvement of the patient's condition, the next day can be infusion, the total number of times does not exceed 5 times
.

06

Applicable population

Can be used early in the course of disease in patients with risk factors for severe disease, high viral load, and rapid disease
progression.

Usage and dosage

The infusion dose is 200-500ml (4-5ml/kg), and it can be decided whether to reinfuse
according to the individual situation of the patient and viral load.

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