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Researchers at Columbia University Mailman School of Public Health and colleagues assessed whether dietary fiber intake was associated with reduced inflammation in older adults and whether fiber was inversely associated with cardiovascular disease
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The results showed that total fiber, especially grain fiber, but not fruit or vegetable fiber, was consistently associated with lower inflammation and lower rates of cardiovascular disease
Data for the study came from a large, well-characterized prospective cohort of older adults and included detailed data on dietary intake, inflammation, and cardiovascular disease incidence
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The study confirms previously observed links between dietary fiber and cardiovascular disease and extends these studies to include sources of fiber, the relationship of fiber to multiple markers of inflammation, and whether inflammation mediates the relationship between dietary fiber and cardiovascular disease.
The relationship between vascular disease
Cardiovascular Health Study of 4,125 adults from 1989 to 1990.
Participants received food frequency questionnaires administered to those without cardiovascular disease prevalence registry followed by follow-up visits to develop cardiovascular disease (stroke, myocardial infarction, atherosclerotic heart disease).
Vascular Death), adopted June 2015
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Blood samples were evaluated for markers of inflammation
"Consuming more dietary fiber reduces the risk of cardiovascular disease
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A common hypothesis is that higher fiber intake reduces inflammation, which in turn reduces the risk of cardiovascular disease," said an epidemiology associate at Columbia Mailman College.
While there is data to suggest that fiber in general may act as an anti-inflammatory by improving gut function, improving diet and satiety (eg, reducing fat and total energy intake), and improving lipid and glucose metabolism, Shivakoti points out why The association of grain fiber, but not vegetable or fruit fiber, with lower inflammation is unclear, and further research is needed
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In addition, he noted, it is unclear whether the grain fiber itself or other nutrients in grain fiber-rich foods drive the observed relationship
Shivakoti observes: "Furthermore, we learned that inflammation has only a small role in mediating the inverse association between cereal fiber and cardiovascular disease
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This suggests that factors other than inflammation may play a role in the cardiovascular disease associated with cereal fiber.