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This article is from the NEJM Journal Watch Noninvasive
Electrical Brain Stimulation Might Improve Memory in Older People Noninvasive electrical stimulation of the brain may improve memory in the elderly
Review by Anthony L.
Komaroff, MD
After 4 days of treatment, both short- and long-term memory improved
.
Previous research has shown that new working memories are temporarily stored by neural circuits in one region of the brain, which are then encoded as long-term memories and stored in circuits in
another region of the brain.
Electrical stimulation of these areas of the brain has the potential to improve memory formation, but evidence from previous studies is inconsistent
.
A team of researchers at Boston University hypothesized that using alternating current at specific frequencies to perform repeated transcranial electrical stimulation of these two regions of the brain had the potential to improve both types of memory
.
The researchers performed transcranial alternating current stimulation
for 20 minutes per day on 150 elderly people (age range, 65~88 years old) with no known neurological or psychiatric diseases.
It is hypothesized that working memory rapidly improves when specific areas of the parietal cortex are stimulated at low frequencies; Long-term memory improves
rapidly when specific areas of the frontal cortex are stimulated by high frequencies.
These improvements last at least 1 month
.
Stimulation of other areas of the brain, or the use of other frequencies or false stimulation (no current) did not improve memory
.
Commenting on the potential to send specific types of noninvasive electrical stimulation to specific areas of the brain has the potential to improve working and long-term memory
in older adults.
Can these results be reproduced? Can the benefits last longer than 1 month? Is the technique also beneficial for people with mild cognitive impairment and even dementia? These results will be very meaningful
for medical staff and such patients.
Articles that are commented on
.
NEJM Medical Frontiers is translated several times a week, published on the app and official website, and selected 2-3 articles are published
on WeChat.
Copyright Information This article is translated, written or commissioned
by Jiahui Medical Research and Education Group (J-Med) and the New England Journal of Medicine (NEJM).
The full Chinese translation and the figures contained therein are exclusively licensed
by NEJM Group.
If you need to reprint, please leave a message or contact nejmqianyan@nejmqianyan.
cn
.
Unauthorized translation is an infringement and the copyright owner reserves the right to
pursue legal responsibility.
Electrical Brain Stimulation Might Improve Memory in Older People Noninvasive electrical stimulation of the brain may improve memory in the elderly
Review by Anthony L.
Komaroff, MD
After 4 days of treatment, both short- and long-term memory improved
.
Previous research has shown that new working memories are temporarily stored by neural circuits in one region of the brain, which are then encoded as long-term memories and stored in circuits in
another region of the brain.
Electrical stimulation of these areas of the brain has the potential to improve memory formation, but evidence from previous studies is inconsistent
.
A team of researchers at Boston University hypothesized that using alternating current at specific frequencies to perform repeated transcranial electrical stimulation of these two regions of the brain had the potential to improve both types of memory
.
The researchers performed transcranial alternating current stimulation
for 20 minutes per day on 150 elderly people (age range, 65~88 years old) with no known neurological or psychiatric diseases.
It is hypothesized that working memory rapidly improves when specific areas of the parietal cortex are stimulated at low frequencies; Long-term memory improves
rapidly when specific areas of the frontal cortex are stimulated by high frequencies.
These improvements last at least 1 month
.
Stimulation of other areas of the brain, or the use of other frequencies or false stimulation (no current) did not improve memory
.
Commenting on the potential to send specific types of noninvasive electrical stimulation to specific areas of the brain has the potential to improve working and long-term memory
in older adults.
Can these results be reproduced? Can the benefits last longer than 1 month? Is the technique also beneficial for people with mild cognitive impairment and even dementia? These results will be very meaningful
for medical staff and such patients.
Articles that are commented on
Grover S et al.
Long-lasting, dissociable improvements in working memory and long-term memory in older adults with repetitive neuromodulation.
Nat Neurosci 2022 Sep; 25:1237.
(https://doi.
org/10.
1038/s41593-022-01132-3)
NEJM Journal Collection
Published by NEJM Group, NEJM Journal Watch invites internationally renowned doctors to review important papers in the medical field to help doctors understand and apply the latest developments.
NEJM Medical Frontiers is translated several times a week, published on the app and official website, and selected 2-3 articles are published
on WeChat.
Copyright Information This article is translated, written or commissioned
by Jiahui Medical Research and Education Group (J-Med) and the New England Journal of Medicine (NEJM).
The full Chinese translation and the figures contained therein are exclusively licensed
by NEJM Group.
If you need to reprint, please leave a message or contact nejmqianyan@nejmqianyan.
cn
.
Unauthorized translation is an infringement and the copyright owner reserves the right to
pursue legal responsibility.
