"Nobel Prize in Medicine"-Galen Prize will be announced soon!

Article source: Med

Author: Ala Lei

From October 25th to 29th, 2021, the "Galen Week" event is going on

Who is Galen?

As an anatomist, physiologist, clinician and researcher, Galen is the father of modern medicine and pharmacy

At the age of 17, Galen worked as a doctor at the gladiator training ground and went to Rome at the age of 37

The history of the Galen Prize

The Galen Prize was founded in France by a pharmacist named Roland Mehl in 1970 to promote the development of pharmacy

The Galen Prize originated in France and its influence gradually increased

The Galen Award of the United States was established in 2007, and the Galen Award reported in the news now basically refers to the Galen Award of the United States

There are three main awards for the Galen Award: Best Pharmaceutical Agent, Best Biotechnology Product, and Best Medical Technology

Award-winning products over the years (U.

Best drugs: Januvia (trade name: Genoví), sitagliptin tablets; Chantix (trade name: Changpei), varenicline tartrate

Best biotech products: Humira (trade name: Xiu Mei Le), Adalimumab; Gardasil (trade name: Jia Da Xiu), HPV vaccine

Year 2008

Best drug: Isentress (trade name: Ai Shengte), namely Lategravir, HIV drug; Selzentry, namely maraviroc, HIV drug

Best biotechnology product: Soliris, which is eculizumab, used for the treatment of hemolytic uremic syndrome, paroxysmal nocturnal hemoglobinuria, myasthenia gravis, etc.

Year 2009

Best drug: Gleevec (trade name: Gleevec), imatinib

The best biotechnology product: Nplate, which is romiplostim (romipristin); Promacta, which is eltrombopag

Best medical technology: Peripheral blood circulating tumor cells (CTCs) analysis system: CellSearch

year 2010

Best drug: Coartem, compound artemether (note: artemisinin-derived drugs), antimalarial drugs

Best biotech product: RotaTeq (trade name: Le Erde), oral rotavirus vaccine
.

Best medical technology: xTAG, a solution for clinical multiple genetic testing
.

On April 8, 2009, the US FDA approved Coartem to treat malaria
.
This is also the first ACT drug to treat malaria and the first Chinese original patent drug registered in the United States
.
Professor Tu Youyou won the Nobel Prize in Physiology or Medicine in 2015 for his discovery of artemisinin
.

year 2011

Best medicine: Prevnar13 (trade name: Prevnar 13), pneumococcal vaccine
.

Best biotechnology product: Stelara (trade name: Starnox), which is usinumumab, used for the treatment of psoriasis, Crohn's disease, etc.
; Prolia and XGEVA, both are denosumab (desulumab) for osteoporosis, bone metastasis of cancer, such as giant cell tumor treatment
.

2012

Best Drugs: Victrelis, i.
e.
of boceprevir (boceprevir); Incivek, i.
e.
of telaprevir (Telapuwei); both drugs are used to treat chronic hepatitis C
.

Best Biotechnology Product: Yervoy (trade name: Yi Wo), that Iraq horses adalimumab for the treatment of melanoma, renal cell cancer, lung cancer and other
.

Best medical technology: Sapien, heart valve; Melody, pulmonary valve
.

In 2012 and 2014, the Galen Prize was awarded to hepatitis C treatment drugs
.
Harvey James Alter, Michael Houghton, Charles M.
Rice, these three scientists who have made important contributions to the hepatitis C virus, won the 2020 No.
Bell Prize in Physiology or Medicine
.

year 2013

Best Drugs: Zelboraf, i.
e.
vemurafenib (vemurafenib), the BRAF inhibitors, for melanoma, Erdheim-Chester disease treatment
.

Best biotech product: Zostavax, shingles vaccine
.

Best medical technology: S-ICD system, cardiac defibrillator
.

Year 2014

Best drug: Sovaldi (trade name: Suo Hua Di), namely sofosbuvir (Sofosbuvir), hepatitis C treatment drug
.

Best biotech product: HEMACORD, cord blood stem cell product
.

Best medical technology: Trevo ProVue, a fully visualized thrombus removal device
.

2015

Best drug: IMBRUVICA (trade name: Yike), that is, ibrutinib, a BTK inhibitor.
The current main indication is hematological tumors
.

Best biotech products: OPDIVO (trade name: Odivo), Navulimab; KEYTRUDA (trade name: Kerida), Pembrolizumab
.

Best medical technology: T2Candida Panel, medical equipment for detecting sepsis
.

Everyone is familiar with "K medicine" and "O medicine"
.
James P.
Allision and Tasuku Honjo won the 2018 Nobel Prize in Physiology or Medicine for discovering cancer treatments that inhibit negative immunomodulation
.

2016

Best drugs: Ibrance (trade name: Aiboxin), palbociclib (pibecili), CDK4/6 inhibitor
.

Best Biotechnology Product: Cosentyx (trade name: be very good), the Secretary Kuqi You monoclonal antibody, anti-IL-17A monoclonal antibody for psoriasis, the treatment of ankylosing go far
.

Best medical technology: Cologuard, a non-invasive, stool DNA colorectal cancer screening kit
.

2017

Best drug: Venclexta, or venetoclax, a Bcl-2 inhibitor, currently the main indication is hematological tumors
.

Best biotech product: Spinraza, or nusinerse, an antisense therapy for the treatment of spinal muscular atrophy
.

Best medical technology: ExablateNeuro, an ultrasound treatment device for Parkinson's disease tremor
.

2018

Best drug: IDHIFA, or enasidenib, a small molecule inhibitor of IDH2, used for the treatment of acute myeloid leukemia
.

Best biotech products: Yescarta, Kymriah, these are two CAR-T cell therapies
.

Best medical technology: Watchman, left atrial appendage closure system
.

2019 year

Best medicine: Shingrix (trade name: Xin'an Lishi), shingles vaccine
.

Best biotech product: LUXTURNA, gene therapy, treatment of hereditary retinal dystrophy with mutation of RPE65 gene
.

Best medical technology: FreeStyle Liber, a 14-day instant scanning glucose detection system
.

2020 year

Best drug: Pretomanid, a nitroimidazole anti-tuberculosis drug
.

Best biotechnology product: Tegsedi, antisense therapy; Onpattro, RNAi therapy; Vyndaqel, TTR stabilizer
.
These three products are products for the treatment of hereditary transthyretin amyloidosis
.

Best medical technology: MitraClip, transcatheter mitral valve repair system
.

This article refers to the official website of the Galen Award

https://